Identification of 43 novel HLA alleles by PacBio single molecule real-time sequencing in haematopoietic cell donors. | LitMetric

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Identification of 43 novel HLA alleles by PacBio single molecule real-time sequencing in haematopoietic cell donors. | LitMetric

Identification of 43 novel HLA alleles by PacBio single molecule real-time sequencing in haematopoietic cell donors.

Albert J E French Jonathan A M Lucas Michael A Cooper Steven G E Marsh Neema P Mayor

HLA

Anthony Nolan Research Institute, Royal Free Hospital, London, UK.

Published: August 2024

Researchers identified 43 new HLA alleles in blood cell donors through advanced DNA sequencing techniques.
The use of single molecule real-time sequencing allowed for more accurate detection of these alleles.
These findings can improve donor matching for transplants and enhance our understanding of genetic diversity in populations.

A total of 43 novel HLA alleles detected in haematopoietic cell donors using single molecule real-time DNA sequencing.

Download full-text PDF	Source
http://dx.doi.org/10.1111/tan.15645	DOI Listing

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