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Sarcoidosis in Beryllium Exposed Workers: A Case-Case Study.
Am J Ind Med
January 2025
Division of Environmental and Occupational Health Sciences, Department of Medicine, National Jewish Health, Denver, Colorado, USA.
Background: Despite the utility of the beryllium lymphocyte proliferation test (BeLPT), distinguishing sarcoidosis, a disease of unknown etiology, from chronic beryllium disease (CBD), has long posed a diagnostic challenge. It is unclear if beryllium-exposed sarcoidosis cases (Be-exp-Sarc) are clinically distinct from CBD, or are misdiagnosed cases of CBD.
Methods: We performed a case-case study of 40 beryllium-exposed individuals diagnosed with Be-exp-Sarc compared to 40 frequency-matched CBD cases.
Chronic berylliosis disease: uncommon pulmonary granulomas beyond sarcoidosis.
Thorax
October 2024
Thoracic Surgery, SLK-Lungenklinik Lowenstein, Lowenstein, Germany.
Multisystemic Beryllium Disease: An Exceptional Case Revealed by a Urinary Tract Granulomatosis.
Int J Mol Sci
July 2024
Department of Nephrology and Dialysis, Brugmann University Hospital, Université libre de Bruxelles, 1020 Bruxelles, Belgium.
Article Synopsis
- Chronic beryllium disease (CBD) is an interstitial lung condition caused by inhaling beryllium particles, and it can often be confused with sarcoidosis but has distinct characteristics and complications.
- A case involving a 60-year-old man revealed multi-organ involvement, with his kidney issues stemming from CBD rather than typical pulmonary symptoms, which were relatively mild.
- The report emphasizes the need for healthcare providers to consider CBD as a potential diagnosis in patients exhibiting granulomatous diseases, especially when they present with related respiratory issues, despite the absence of classical lung symptoms.
In Response to: Re: TenHarmsel et al., Mortality Among Individuals Diagnosed With Chronic Beryllium Disease and Beryllium Sensitization.
J Occup Environ Med
July 2024
Division of Occupational and Environmental Medicine, Department of Medicine, College of Human Medicine, Michigan State University, East Lansing, Michigan.
Re: TenHarmsel et al., Mortality Among Individuals Diagnosed With Chronic Beryllium Disease and Beryllium Sensitization.
J Occup Environ Med
July 2024
Stony Brook Cancer Center, Stony Brook University, Stony Brook, NY.
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