Microbiome modification for personalized treatment of dysbiotic diseases.

Cell Host Microbe

Center for Gastrointestinal Biology and Disease, University of North Carolina - Chapel Hill, Chapel Hill, NC 27517, USA. Electronic address:

Published: August 2024

Fecal microbial transplantation (FMT) for inflammatory diseases or refractory immune checkpoint inhibitor therapy is less effective than for preventing recurrent Clostridioides difficile infection. This commentary outlines strategies to use biomarkers of successful FMT to guide newer approaches to restore microbial homeostasis in individuals with dysbiosis-mediated inflammation.

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Source
http://dx.doi.org/10.1016/j.chom.2024.07.023DOI Listing

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