We present the highest, to the best of our knowledge, average power from a laser-driven single-cycle THz source demonstrated so far, using optical rectification in the tilted pulse front geometry in cryogenically cooled lithium niobate, pumped by a commercially available 500 W ultrafast thin-disk ytterbium (Yb) amplifier. We study repetition rate-dependent effects in our setup at 100 and 40 kHz at this high average power, revealing different optimal fluence conditions for efficient conversion. The demonstrated sources with multi-100 mW average power at these high repetition rates combine high THz pulse energies and high repetition rate and are thus ideally suited for nonlinear THz spectroscopy experiments with significantly reduced measurement times. The presented result is a first benchmark for high average power THz time-domain spectroscopy systems for nonlinear spectroscopy, driven by very high average power ultrafast Yb lasers.
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http://dx.doi.org/10.1364/OL.532219 | DOI Listing |
BMC Genomics
December 2024
Pathology and Biomedical Science Department, University of Otago Christchurch, Christchurch, New Zealand.
Background: Anorexia nervosa (AN) is a polygenic, severe metabopsychiatric disorder with poorly understood aetiology. Eight significant loci have been identified by genome-wide association studies (GWAS) and single nucleotide polymorphism (SNP)-based heritability was estimated to be ~ 11-17, yet causal variants remain elusive. It is therefore important to define the full spectrum of genetic variants in the wider regions surrounding these significantly associated loci.
View Article and Find Full Text PDFClin Transplant
January 2025
Gastro-Intestinal Rehabilitation and Transplant Center - GIRTC, Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Background: There has been significant concern about coronavirus disease 2019 (COVID-19) among transplant recipients, particularly those who are highly immunosuppressed. Several studies have analyzed the impact of COVID-19 on different solid organ transplant patients. However, few isolated case reports of COVID-19 in intestinal and multivisceral transplant (ITx and MVTx) recipients are available in the literature.
View Article and Find Full Text PDFEnviron Technol
December 2024
College of Mechanical and Electrical Engineering, China Jiliang University, Hangzhou, People's Republic of China.
The moisture content (MC) of sludge is a critical factor affecting sludge treatment and disposal technologies. Traditional drying methods for measuring sludge MC are time-consuming and lack of portability. To achieve rapid online detection of sludge MC, this paper proposes a method based on frequency domain reflectometry.
View Article and Find Full Text PDFSci Rep
December 2024
North China University of Water Resources and Electric Power, Zhengzhou, 450046, China.
The long-standing problem of geometric problem solving in artificial intelligence education has attracted widespread attention. It is necessary to combine geometry diagrams and text descriptions to form a logical representation. This involves combining the knowledge of mathematical theorems, generating a solution sequence, and executing to obtain the answer.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Biomedical Engineering, Faculty of Applied Science, Ho Chi Minh City University of Technology (HCMUT), 268 Ly Thuong Kiet, District 10, Ho Chi Minh City, 700000, Vietnam.
This study addresses the growing importance of hand gesture recognition across diverse fields, such as industry, education, and healthcare, targeting the often-neglected needs of the deaf and dumb community. The primary objective is to improve communication between individuals, thereby enhancing the overall quality of life, particularly in the context of advanced healthcare. This paper presents a novel approach for real-time hand gesture recognition using bio-impedance techniques.
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