Evaluation of Patients with Painful Ophthalmoplegia for Benign and Secondary Etiologies.

Neuroophthalmology

Department of Neurology, Algology, Adnan Menderes University, Aydin, Turkey.

Published: April 2024

This study aims to establish the final definite etiology among patients with long-term follow-up for painful ophthalmoplegia. The data of 44 cases (16 females, 28 females) were examined. In the first diagnosis, subjects were scanned in terms of benign and secondary etiologies. Clinical and radiological follow-up results of patients were recorded. During the follow-up period, data on clinical outcomes (relapse or progression), treatment responses, and final diagnoses were evaluated In total, 49 episodes of painful ophthalmoplegia (44 patients) were evaluated. Secondary etiologies were identified in 21 patients benign/secondary tumours causes in 10, inflammatory in 1, infectious in 3, vascular in 3, demyelinating disease in 1, autoimmune in 2, drug-related cause in 1. 23 patients with benign etiologies; 11 had Tolosa-Hunt syndrome (THS), 2 had Recurrent Painful Ophthalmoplegic Neuropathy (RPON), and 10 had diabetic ophthalmoparesis (DO). 7 of 11 patients with THS met the International Classification Headache Disorders 3rd edition (ICHD-3 beta) criteria, 4 were with a normal MRI, and 1 had a recurrence. 9 of 10 patients with benign/secondary tumours causes were malignant, and 7 died due to disease progression during the treatment process. One of ten patient was followed with diabetic ophthalmoparesis and was diagnosed with cavernous sinus involvement of B-cell lymphoma as a result of clinical progression during follow-up. Painful ophthalmoplegia is a complex clinical condition with a broad differential diagnosis with malignant and benign etiologies. A detailed clinical examination, imaging, and long-term follow-up are essential for accurate diagnosis and treatment management.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11321404PMC
http://dx.doi.org/10.1080/01658107.2024.2336270DOI Listing

Publication Analysis

Top Keywords

painful ophthalmoplegia
16
secondary etiologies
12
benign secondary
8
long-term follow-up
8
follow-up painful
8
progression treatment
8
patients benign/secondary
8
benign/secondary tumours
8
benign etiologies
8
diabetic ophthalmoparesis
8

Similar Publications

Rhino-orbital-cerebral mucormycosis (ROCM) is an opportunistic infection that has increased due to COVID-19 with the use of corticosteroids and diabetes being the most important predisposing factors. Orbital apex syndrome with central retinal artery occlusion secondary to mucormycosis is relatively rare. This case report highlights a case of a 62-year-old female with poorly controlled diabetes and a history of COVID-19 two weeks prior, who presented with acute right eye painful visual loss for three days associated with bulging of the right eye and drooping of the eyelid.

View Article and Find Full Text PDF

An Atypical Case of Orbital Wall Infarction Secondary to Sickle Cell Disease in an Adult and Review of Literature.

Ophthalmic Plast Reconstr Surg

December 2024

Moorfields Eye Hospital NHS Foundation Trust, Moorfields Eye Hospital, London, United Kingdom.

Sickle cell disease is known to cause painful vaso-occlusive crises in long bones with large marrows. Orbital infarction is a rare complication of sickle cell disease and usually presents in children and adolescents with acute onset periocular swelling mimicking orbital cellulitis. We describe an atypical case of a 38-year-old man with homozygous sickle cell disease who presented with isolated, complete ptosis of his OD with minimal swelling.

View Article and Find Full Text PDF

Spatial discrimination in patients with MSA, PSP, DIP, and VP with pain.

Sci Rep

December 2024

Department of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, 7, Keunjaebong-gil, Hwaseong, Gyeonggi-do, 18450, Republic of Korea.

Article Synopsis
  • * A study involving 79 patients revealed high percentages of pain in MSA (73.9%), PSP (50.0%), DIP (67.9%), and VP (66.7%), but found no significant differences in sensory discrimination thresholds (SDT) between those with and without pain.
  • * The research concluded that the scaling function did not play a significant role in the development of pain among the different parkinsonian disorders studied.
View Article and Find Full Text PDF

Expanded Endoscopic Endonasal Clipping of a Giant Cavernous Carotid Aneurysm.

World Neurosurg

December 2024

Saint Alphonsus Medical Group, Trinity Healthcare System, Boise, Idaho, USA.

Cavernous carotid aneurysms are typically small, asymptomatic, and often do not require treatment. We present the case of a 59-year-old woman, a 3-pack-a-day smoker, who presented with the primary complaint of left retro-orbital pain, left complete ophthalmoplegia, left-sided blindness, and right abducens palsy. Imaging revealed a giant right cavernous carotid aneurysm, which had expanded to the contralateral cavernous sinus wall and superiorly through the diaphragm sellae.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!