The teaching of Chinese as a second language has become increasingly crucial for promoting cross-cultural exchange and mutual learning worldwide. However, traditional approaches to international Chinese language teaching have limitations that hinder their effectiveness, such as outdated teaching materials, lack of qualified instructors, and limited access to learning facilities. To overcome these challenges, it is imperative to develop intelligent and visually engaging methods for teaching international Chinese language learners. In this article, we propose leveraging speech recognition technology within artificial intelligence to create an oral assistance platform that provides visualized pinyin-formatted feedback to learners. Additionally, this system can identify accent errors and provide vocational skills training to improve learners' communication abilities. To achieve this, we propose the Attention-Connectionist Temporal Classification (CTC) model, which utilizes a specific temporal convolutional neural network to capture the location information necessary for accurate speech recognition. Our experimental results demonstrate that this model outperforms similar approaches, with significant reductions in error rates for both validation and test sets, compared with the original Attention model, Claim, Evidence, Reasoning (CER) is reduced by 0.67%. Overall, our proposed approach has significant potential for enhancing the efficiency and effectiveness of vocational skills training for international Chinese language learners.
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http://dx.doi.org/10.7717/peerj-cs.2223 | DOI Listing |
Cell Metab
January 2025
Henan Academy of Sciences, Zhengzhou 450000, China; Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. Electronic address:
Cellular senescence, a hallmark of aging, involves a stable exit from the cell cycle. Senescent cells (SnCs) are closely associated with aging and aging-related disorders, making them potential targets for anti-aging interventions. In this study, we demonstrated that human embryonic stem cell-derived exosomes (hESC-Exos) reversed senescence by restoring the proliferative capacity of SnCs in vitro.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2025
Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China, Yangzhou University, Yangzhou, China; Key Laboratory of Animal Breeding Reproduction and Molecular Design for Jiangsu Province, College of Animal Science and Technology, Yangzhou University, Yangzhou, China. Electronic address:
Aflatoxins harm the reproductive system and gamete development in animals. Primordial germ cells (PGCs) in chickens, as ancestral cells of gametes, are essential for genetic transmission, yet the impact and mechanisms of aflatoxins on them remain elusive. This study systematically investigated the effects of aflatoxin B1 (AFB1) on chicken PGCs and their potential mechanisms using an in vitro culture model.
View Article and Find Full Text PDFJ Environ Manage
January 2025
Management Science Institute, Hohai University, Nanjing, 210098, China.
Residents' satisfaction perceptions of ecosystem services (ESs) are essential for the ecological protection and high-quality development of the Yellow River Basin (YRB). Existing studies lacks large-scale survey of local residents' satisfaction perception at urban scale within river basins, and has not effectively explored the matching relationship between the ESs supply and the perceptions of local residents. To address this gap, this study develops a database on nine ESs supply and individual perceptions of the YRB, constructs a comprehensive framework to quantify the matching of ESs supply and local residents' satisfaction perceptions, and proposes targeted strategy.
View Article and Find Full Text PDFEur J Med Chem
January 2025
State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, #345 Lingling Rd, Shanghai, 200032, China. Electronic address:
The pseudokinase HER3 emerges as a promising anti-cancer target, especially for HER2-driven breast cancer and EGFR-mediated non-small cell lung cancer. However, it is challenging to target HER3 by ATP-competitive small molecules because HER3 is catalytically impaired. Herein, we report the discovery of a series of HER3 degraders by connecting a HER3 binder bosutinib with a hydrophobic tag adamantane.
View Article and Find Full Text PDFSeizure
January 2025
Department of Neurology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China. Electronic address:
Objective: To translate and validate the Chinese version of the Epilepsy Anxiety Survey Instrument (EASI) and its brief version (brEASI) among Chinese people with epilepsy.
Methods: Adult outpatients from Sichuan Provincial People's Hospital were recruited. The type of anxiety disorder was determined via the Mini International Neuropsychiatric Interview (MINI).
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