AI Article Synopsis
- Researchers created new ferrocenyl-related compounds using a chemical reaction between arynes and ferrocenyl oxazolines under mild conditions.
- Water played a surprising role in rearranging these compounds into quinoline structures, while theoretical calculations confirmed the processes involved.
- This study introduces two new methods that enhance the interaction of ferrocenyl compounds with arynes, paving the way for innovative ferrocene derivative synthesis.
Article Abstract
Ferrocenyl conjugated oxazepine/quinoline derivatives were presented through the reaction of hexadehydro-Diels-Alder (HDDA) generated arynes with ferrocenyl oxazolines under mild conditions ring-expanding or rearrangement processes. Water molecule participated in this unexpected rearrangement process to produce quinoline skeletons, and DFT calculations supported a ring-expanding and intramolecular hydrogen migration process for the formation of oxazepine derivatives. Two variants of this chemistry, expanded the reactivity between ferrocenyl conjugated substances and arynes, further providing an innovative approach for the synthesis of ferrocene derivatives.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11322062 | PMC |
| http://dx.doi.org/10.3389/fchem.2024.1441539 | DOI Listing |
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