Aim: The aim of the study was to determine the efficacy of commercially available immunoglobulin Y (IgY) chewable tablets on () count in patients undergoing orthodontic treatment.
Materials And Methods: Participants aged between 12 and 19 years who had fixed, nonextraction orthodontic treatment with no carious lesion were included in the study and advised to take IgY chewable tablet for 15 days (one course) and saliva samples were collected from the patients on day 61, 91, and 121 days from the placement of fixed appliance, to assess its ability in reduction of count The collected samples were processed, and levels were estimated. The results were tabulated and subjected to statistical analysis using Statistical Package for the Social Sciences (SPSS) version 20, and the repeated measures test was used to compare different groups.
Results: Immunoglobulin Y (IgY) chewable tablet was found to be significantly effective in decreasing counts in patients undergoing orthodontic treatment during the study period.
Conclusion: Oral passive immunotherapy egg yolk antibody IgY effectively decreased the level, which was found to increase during orthodontic fixed appliance treatment.
Clinical Significance: The IgY chewable tablets can be used as an adjuvant to reduce counts and provide basic oral hygiene measures.
How To Cite This Article: Muthukumaran M, Jayaprakash J, Arangannal P, Efficacy of Immunoglobulin Y Chewable Tablets on Count in Patients Undergoing Orthodontic Treatment. Int J Clin Pediatr Dent 2024;17(3):265-269.
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http://dx.doi.org/10.5005/jp-journals-10005-2774 | DOI Listing |
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Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.
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Physiopathology Department, George Emil Palade University of Medicine, Pharmacy, Sciences and Technology, 540142 Targu Mures, Romania.
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Unicycive Therapeutics, Inc., Los Altos, CA.
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November 2024
Department of Pharmaceutical Engineering, Cheongju University, Cheongju 28503, Republic of Korea.
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