Aim: The study aimed to evaluate and compare the antimicrobial efficacy of (0.5%) mouthwash, (0.5%) mouthwash, and 0.12% chlorhexidine gluconate mouthwash against
Materials And Methods: A total of 60 samples of the five mouthwash preparations were prepared to check for their antimicrobial efficacy. The zone of inhibition (ZOI) against was measured as a diameter in mm, and the minimum inhibitory concentration (MIC) of mouthwash preparations was measured as μg/mL. All the groups were compared statistically using the Mann-Whitney test and the Kruskal-Wallis test.
Results: The highest ZOI was observed in group V chlorhexidine gluconate [mean: 20.8, standard deviation (SD): 0.58], followed by group III (alcohol-free) (mean: 15.5, SD: 0.67), group IV (alcohol-based) (mean: 14.08, SD: 0.66), and group II (alcohol-based) (mean: 13.2, SD: 0.45). The least ZOI was observed in group I (alcohol-free) (mean: 10.7, SD: 0.45). This difference was statistically significant ( < 0.01). The MIC was similar in all the groups ( = 0.13).
Conclusion: Chlorhexidine gluconate 0.12% mouthwash showed the best antimicrobial action; however, mouthwash showed potential against mouthwash exhibited limited antimicrobial activity.
How To Cite This Article: Deolikar S, Jawdekar A, Saraf T, Comparative Evaluation of the Antimicrobial Efficacy of (0.5%) Mouthwash, (0.5%) Mouthwash, and 0.12% Chlorhexidine Gluconate Mouthwash against An Study. Int J Clin Pediatr Dent 2024;17(4):461-466.
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| http://dx.doi.org/10.5005/jp-journals-10005-2832 | DOI Listing |
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