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http://dx.doi.org/10.21037/qims-23-1585 | DOI Listing |
Significance: Coronary artery disease is the leading cause of death worldwide, accounting for 16% of all deaths. A common treatment is coronary artery bypass grafting (CABG), though up to 12% of bypass grafts fail during surgery. Early detection of graft failure by intraoperative graft patency assessment could prevent severe complications.
View Article and Find Full Text PDFFront Cell Infect Microbiol
March 2025
Department of Clinical Laboratory, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Laboratory, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Objective: Bloodstream infections(BSIs) caused by carbapenem-resistant (CRAB) have a high mortality rate due to the high levels of drug resistance. There is an urgent need to establish a sensitive and accurate detection method to rapidly detect CRAB in BSIs.
Methods: A new method was developed based on fluorescence quantitative PCR (qPCR) targeting the specific region of 16sRNA and OXA-23 gene from CRAB.
Int J Nanomedicine
March 2025
Department of Periodontics and Mucosa, The second Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, 121000, People's Republic of China.
Introduction: Periodontitis is the most common non-communicable disease in humans. The main challenge in the treatment of periodontitis is to effectively control periodontal inflammation and promote tissue repair. Human umbilical cord mesenchymal stem cells-derived exosomes (hucMSCs-exo) have been reported to modulate inflammatory responses and promote tissue repairment mainly through miRNAs in several diseases.
View Article and Find Full Text PDFFront Neuroergon
February 2025
Department of Radiological Technology, Faculty of Medical Technology, Niigata University of Health and Welfare, Niigata, Japan.
Introduction: Recently, a link has been established between cognitive function and hand dexterity in older adults. Declines in cognitive function have been shown to impair performance in finger tapping movements. Research suggest that hand training can improve dexterity, executive function, and cognitive function over time.
View Article and Find Full Text PDFClin Transl Med
March 2025
Department of Gastroenterology, Endoscopy Center, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
Background: Oesophageal squamous cell carcinoma (OSCC) is a highly lethal cancer characterized by its aggressive nature and chemotherapy resistance. Peptidylarginine deiminase 4 (PADI4) regulates protein citrullination and is associated with various cancer developments. The role of PADI4 in OSCC progression and chemoresistance remains unexplored.
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