ZFP318 fuels memory B cells for success.

Immunity

Immunology Program, Babraham Institute, Cambridge, UK. Electronic address:

Published: August 2024

Diversity is a key feature of B cell biology-from BCR rearrangement to the heterogeneity of memory B cells. In this issue of Immunity, Wang et al. show that the zinc-finger protein ZFP318 supports mitochondrial health in certain memory B cells, thereby facilitating potent recall upon rechallenge.

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http://dx.doi.org/10.1016/j.immuni.2024.07.017DOI Listing

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