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http://dx.doi.org/10.1212/NXI.0000000000200297 | DOI Listing |
Neurol Neuroimmunol Neuroinflamm
November 2024
From the Department of Neurology (K.S., S.S., F.B.V., A.P.), University Hospital of Basel; and Department of Clinical Research (K.S., S.S., F.B.V., A.P.), Faculty of Medicine, University and University Hospital of Basel, Switzerland.
Am J Ophthalmol Case Rep
March 2021
Duke University, Department of Ophthalmology, Durham, NC, USA.
Purpose: Traumatic injury to the optic chiasm is rare and most frequently caused by high-velocity head trauma. It classically results in bitemporal hemianopsia and often presents in conjunction with multiple other traumatic injuries, such as skull fractures and cerebrospinal fluid leaks. We present the case of a 40-year-old woman with pre-existing thyroid orbitopathy who struck her forehead after a fall from standing height.
View Article and Find Full Text PDFJ Neurol Sci
December 2020
Department of Neurology, New York University Grossman School of Medicine, New York, NY, USA; Department of Ophthalmology, New York University Grossman School of Medicine, New York, NY, USA. Electronic address:
Objective: Investigations have found associations of homonymous thinning of the macular ganglion cell/ inner-plexiform layer (GCIPL) with demyelinating lesions in the post-chiasmal visual pathway among patients with multiple sclerosis (MS). Retinal thinning may also occur through retrograde trans-synaptic degeneration, a process by which lesions in post-geniculate visual pathway structures lead to thinning of the GCIPL across thalamic synapses. The purpose of our study was to determine the frequency of homonymous hemimacular thinning that occurs in association with post-chiasmal visual pathway demyelinating lesions in patients with MS and other demyelinating diseases.
View Article and Find Full Text PDFJ Neurol Sci
October 2020
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada; Kensington Vision and Research Centre, Toronto, Ontario, Canada. Electronic address:
Homonymous hemimacular thinning of the retinal ganglion cell-inner plexiform layer (GCIPL) on optical coherence tomography (OCT) in the absence of significant visual field defects may be identified in the workup of patients with visual complaints, but the causes of this finding remain unknown. We retrospectively reviewed 1425 consecutive patients referred for neuro-ophthalmic assessment who had high quality OCT scans and reliable Humphrey 24-2 SITA-Fast testing. A total of 7 patients, 3 females and 4 males, with a mean age of 39.
View Article and Find Full Text PDFMedicine (Baltimore)
August 2016
Department of Ophthalmology and Visual Science, Eye, Ear, Nose and Throat Hospital, Shanghai Medical College, Fudan University Key Laboratory of Myopia, Ministry of Health (Fudan University) Shanghai Key Laboratory of Visual Impairment and Restoration (Fudan University) State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Fudan University, Shanghai, China.
To evaluate and compare macular microvasculature changes in eyes with primary open-angle glaucoma (POAG) to normal eyes, and to assess associations among the retinal microvasculature, neural structural damage, and visual field loss.Ninety-nine eyes (68 patients with POAG and 31 normal subjects) were enrolled in this study. Thirty-five eyes with early-stage glaucoma (EG), 33 eyes with advanced-stage glaucoma (AG), and 31 normal eyes were included.
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