Current research progress on and associated diseases.

Crit Rev Microbiol

Key Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Key Laboratory of Pollution Exposure and Health Intervention of Zhejiang Province, Shulan International Medical College, Zhejiang Shuren University, Hangzhou, Zhejiang, China.

Published: August 2024

AI Article Synopsis

  • This text discusses a Gram-negative anaerobic bacterium that is a common cause of periodontitis and is linked to different diseases affecting multiple systems.
  • It highlights the bacterium's virulence factors like cysteine protease and adhesins, which help it bind to and invade host cells such as gingival fibroblasts.
  • The article reviews research on these virulence factors and their role in bacterial pathogenesis, as well as the connection between the bacterium and various diseases.

Article Abstract

is a Gram-negative anaerobic bacterium that is a common pathogen of periodontitis. Recent studies have revealed that is closely associated with a variety of diseases involving multiple systems. Under the action of its virulence factors such as cysteine protease and adhesins, has the ability to bind and invade various host cells including gingival fibroblasts. It can also copolymerize a variety of pathogenic bacteria, leading to interference with the host's immune inflammatory response and causing various diseases. In this article, we review the progress of research on virulence factors and bacterial pathogenesis, and the correlation between and various diseases.

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Source
http://dx.doi.org/10.1080/1040841X.2024.2390594DOI Listing

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