Purpose: To present a set of closed-form analytical equations to create a consistent eye model balance based on clinically measured input parameters in a single step. These models complement the existing iterative approaches in the literature.
Methods: Two different approaches are presented, both considering the cornea and lens as equivalent thin lenses. The first, called the Gaussian model, starts by defining the refractive error as the difference between the axial power (or dioptric distance) and the whole eye power, which can be expanded by filling in the formulas for each power. The resulting equation can be solved for either the refractive error, axial length, corneal power, lens power or the distance between the cornea and the lens as a function of the other four parameters. The second approach uses vergence calculations to provide alternative expressions, assuming that the refractive error is located at the corneal plane. Both models are explored for a biometric range typically found in adult human eyes.
Results: The Gaussian and vergence models each instantly balance the input data into a working eye model over the human physiological range and far beyond as demonstrated in various examples. The equations of the Gaussian model are more complicated, while the vergence model experiences more singularities, albeit in trivial or highly unlikely parameter combinations.
Conclusions: The proposed equations form a flexible and robust platform to create eye models from clinical data. Possible applications lie in creating animal eye models or providing a generic reference for real biometric data and the relationships between the ocular dimensions.
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http://dx.doi.org/10.1111/opo.13376 | DOI Listing |
Invest Ophthalmol Vis Sci
January 2025
School of Psychology and Public Health, La Trobe University, Melbourne, Australia.
Purpose: Prolonged exposure to broadband light with a short-wavelength (blue) or long-wavelength (orange/red) bias is known to impact eye growth and refraction, but the mechanisms underlying this response are unknown. Thus, the present study investigated the effects of broadband blue and orange lights with well-differentiated spectrums on refractive development and global flash electroretinography (gfERG) measures of retinal function in the chick myopia model.
Methods: Chicks were raised for 4 days with monocular negative lenses, or no lens, under blue, orange, or white light.
Background: To determine whether accounting for posterior corneal surgically induced astigmatism (SIA) would improve toric intraocular lens power calculation prediction error.
Methods: A total of 189 eyes of 148 patients undergoing routine cataract surgery were included in the study. Standard and posterior keratometry were measured pre- and postoperatively.
BMJ Open Ophthalmol
January 2025
Department of Eye and Vision Science, University of Liverpool, Liverpool, UK.
Purpose: To quantify the effect of cataract surgery on cornea shape.
Methods: Patients undergoing cataract surgery with standardised 2.75 mm surgical incisions at 110 degrees with a side port at 50 degrees were included.
Photodiagnosis Photodyn Ther
January 2025
Istanbul Medeniyet University, Faculty of Medicine, Department of Ophthalmology, Istanbul, Turkey. Electronic address:
Objective: Imaging techniques have demonstrated changes in the choroid and retina in acute central serous chorioretinopathy (CSCR), but the effects on the optic nerve head (ONH) remain unclear. This study investigates ONH structural changes in acute CSCR using enhanced deep imaging optic coherence tomography (EDI-OCT).
Methods: A prospective cohort study included 51 acute CSCR patients and 51 healthy controls aged 18-65 years.
BMJ Open Ophthalmol
December 2024
Ophthalmology, Royal Hospital for Children, Glasgow, UK.
Background: Very premature infants screened for retinopathy of prematurity (ROP) that do not develop ROP still experience serious visual developmental challenges, and while it is recommended that all children in the UK are offered preschool visual screening, we aimed to explore whether this vulnerable group requires dedicated follow-up.
Methods: We performed a real-world retrospective observational cohort study of children previously screened for ROP in NHS Greater Glasgow and Clyde (Scotland) between 2013 and 2015. We excluded those with any severity of ROP identified during screening.
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