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Comparison of Biocompatibility of 3D-Printed Ceramic and Titanium in Micropig Ankle Hemiarthroplasty.
Biomedicines
November 2024
Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.
Background: Ankle arthritis is a common degenerative disease that progresses as cartilage damage in the lower tibia and upper talus progresses, resulting in loss of joint function. In addition to typical arthritis, there is also structural bone loss in the talus due to diseases such as talar avascular necrosis. Total talus replacement surgery is the procedure of choice in end-stage ankle arthritis and consists of a tibial, talar component and an insert.
View Article and Find Full Text PDFIntegrated psychosocial support in the ICU.
Curr Opin Anaesthesiol
February 2025
Department of Developmental Pediatrics.
Article Synopsis
- The ICU environment exposes patients, relatives, and staff to traumatic experiences, prompting the need for effective mental health support to mitigate adverse effects.
- Current mental health services in healthcare systems typically react to existing conditions, making them less effective for prevention; integrated psychosocial support (IPS) models show promise by incorporating psychologists directly into ICU teams.
- Psychologists in the ICU can identify and address mental health issues early, enhancing support for patients and staff, and improving the overall resilience of the ICU team.
Temporal ablation of the ciliary protein IFT88 alters normal brainwave patterns.
Sci Rep
January 2025
Department of Molecular, Cellular, and Biomedical Sciences, College of Life Sciences and Agriculture, University of New Hampshire, Durham, NH, 03824, USA.
Article Synopsis
- The primary cilium is a crucial organelle involved in various signaling pathways, and its dysfunction is linked to conditions like Bardet-Biedl syndrome, Alzheimer's, and autism, all of which can lead to cognitive impairment.
- Researchers studied the effects of temporarily disabling the IFT88 gene, vital for cilia formation, in adult mice to understand cilia's role in brain activity.
- The findings showed that mice lacking functional cilia had significant learning deficits and abnormal brainwave patterns, emphasizing the importance of primary cilia for proper neural function and memory in adults.
Lactate improves postoperative cognitive function through attenuating oxidative stress and neuroinflammation in aged mice via activating the SIRT1 pathway.
Exp Neurol
December 2024
Department of Anesthesiology, surgery and pain management, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China. Electronic address:
Postoperative cognitive dysfunction (POCD) is a recognized clinical phenomenon characterized by cognitive impairment in patients following anesthesia and surgery, especially in the elderly. However, the pathogenesis of POCD remains unclear. In the last decades, lactate's neuroprotective properties have been increasingly mentioned.
View Article and Find Full Text PDFLongitudinal volumetric analysis of compartments in chicken eggs using ultra-high-field magnetic resonance imaging.
Front Vet Sci
December 2024
Department of Ophthalmology, Rostock University Medical Center, Rostock, Germany.
Introduction: The chicken egg, with its compartments, is a widely used and popular animal model in experimental studies. This study aimed to quantify the volumes of the yolk/yolk sac, amniotic fluid, and chicken embryo using non-invasive ultra-high-field magnetic resonance imaging (UHF-MRI).
Materials And Methods: In total, 64 chicken eggs were examined using a 7 T UHF-MRI scanner, acquiring T2-weighted anatomical images of the entire egg from developmental day 1 to 16 (D1-D16).
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