Portable Voltammetry: A Rapid and Efficient Technique for Determining UV Filters in Cosmetics: A Comparative Study with HPLC-PDA and HPLC-MS/MS.

This study addresses the widespread use of UV filters (UVFs) in cosmetic and solar products due to the negative effects of UV radiation, particularly in relation to melanoma risk. While these filters offer protection, their extensive application raises concerns about their environmental and health impacts. Organic UVFs, in particular, have been associated with endocrine disruption in aquatic species and coral reef damage. To mitigate these concerns, regulatory limits have been imposed on certain UVFs. Current analytical techniques for UVF determination, such as HPLC-PDA and HPLC-MS/MS, offer high accuracy but are expensive and lack on-site monitoring capabilities. In response, this research aims to develop a rapid and cost-effective method, utilizing voltammetry for organic UVF quantification in complex matrices like sunscreens. Additionally, HPLC-PDA and HPLC-MS/MS are employed for electrochemical methods and device validation. This approach not only addresses the need for efficient UVF analysis but also provides a basis for regulatory compliance and environmental stewardship in the cosmetics industry.