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http://dx.doi.org/10.1111/jgs.19126 | DOI Listing |
J Am Geriatr Soc
October 2024
Rory Meyers College of Nursing, New York University, New York, New York, USA.
Aging Cell
August 2024
Institute for Biomedical Aging Research, University of Innsbruck, Innsbruck, Austria.
Skin aging is the result of two types of aging, "intrinsic aging" an inevitable consequence of physiologic and genetically determined changes and "extrinsic aging," which is dependent on external factors such as exposure to sunlight, smoking, and dietary habits. UVB causes skin injury through the generation of free radicals and other oxidative byproducts, also contributing to DNA damage. Appearance and accumulation of senescent cells in the skin are considered one of the hallmarks of aging in this tissue.
View Article and Find Full Text PDFJ Biomed Res
February 2024
Chongqing Medical University, Chongqing 400042, China.
Aging is characterized by progressive degeneration of tissues and organs, and it is positively associated with an increased mortality rate. The brain, as one of the most significantly affected organs, experiences age-related changes, including abnormal neuronal activity, dysfunctional calcium homeostasis, dysregulated mitochondrial function, and increased levels of reactive oxygen species. These changes collectively contribute to cognitive deterioration.
View Article and Find Full Text PDFBackground: The global increase in human life expectancy is evident. The total number of individuals aged 60 or above is anticipated to reach 2 billion by 2050. Aging, an inherently complex process, manifests prominently in the changes observed in the immune system.
View Article and Find Full Text PDFAm J Physiol Heart Circ Physiol
April 2024
Philips Research, Eindhoven, The Netherlands.
Cardiovascular aging is strongly associated with increased risk of cardiovascular disease and mortality. Moreover, health and lifestyle factors may accelerate age-induced alterations, such as increased arterial stiffness and wall dilation, beyond chronological age, making the clinical assessment of cardiovascular aging an important prompt for preventative action. Carotid flow waveforms contain information about age-dependent cardiovascular properties, and their ease of measurement via noninvasive Doppler ultrasound (US) makes their analysis a promising tool for the routine assessment of cardiovascular aging.
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