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driven fluorophores are differentially expressed in and mutant ciliated neurons. | LitMetric

driven fluorophores are differentially expressed in and mutant ciliated neurons.

MicroPubl Biol

Department of Genetics and Human Genetics Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, United States.

Published: July 2024

Intraflagellar transport (IFT) involves the coordinated transport of molecular motors and other proteins and is required for ciliogenesis and ciliary maintenance. The IFT protein OSM-5 /IFT88 is expressed in a majority of the ciliated neurons in the animal, and mutants exhibit structurally defective cilia. The promoter is commonly used to express genetic constructs in the ciliated neurons. In this study, we show that brightness of driven constructs is altered in mutants of the tubulin deglutamylase and the NIMA-related kinase . This raises the possibility that expression levels may be regulated by and .

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318990PMC
http://dx.doi.org/10.17912/micropub.biology.001245DOI Listing

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