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| http://dx.doi.org/10.1111/aogs.14939 | DOI Listing |
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Pregnancy, delivery, and neonatal outcomes among women with beta-thalassemia major: a population-based study of a large US database.
Arch Gynecol Obstet
January 2025
Department of Obstetrics & Gynecology, University of Tabuk, Tabuk, Saudi Arabia.
Purpose: We explored the effect of beta-thalassemia major on pregnancy and delivery outcomes in non-endemic area, utilizing USA population database.
Methods: This is a retrospective study utilizing data from the Healthcare Cost and Utilization Project-Nationwide Inpatient Sample. A cohort of all deliveries between 2011 and 2014 was created using ICD-9 codes.
Contrast-Enhanced Ultrasound Diagnosis of Uterine Myometrial Ischemia Following Myometrial Repair Sutures for Postpartum Hemorrhage Caused by Placenta Accreta.
J Clin Ultrasound
January 2025
Department of Ultrasonic Medicine, West China Second University Hospital of Sichuan University, Chengdu, China.
We report the case of a 28-year-old female patient (gravida 2, para 1) who underwent a cesarean section after 33 weeks of pregnancy due to severe preeclampsia. The placenta was deeply embedded in the myometrium. Localized myometrial ischemia occurred following repair and suturing of the myometrium at the placental attachment site.
View Article and Find Full Text PDFPregnancy Outcomes After Transvaginal Radiofrequency Ablation of Leiomyomas.
Obstet Gynecol
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Division of Minimally Invasive Surgery, Victoria Rey Clinic, Loyola University, Seville, Spain.
Objective: To evaluate pregnancy outcomes after transvaginal radiofrequency ablation of leiomyomas.
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MiR-519d-3p from Placenta-Derived Exosomes Induce Immune Intolerance Regulating Immune Cells, Contributing to the Pathogenesis of Preeclampsia.
Immunol Invest
January 2025
Department of Obstetrics and Gynecology, Medical Centre of Maternity and Child Health, Shengli Clinical Medical College of Fujian Medical University, Fujian, China.
Background: MiR-519d-3p, also called specific placenta biomarkers, is a member of the Chromosome 19 miRNA Cluster (C19MC) with the highest concentrations of miRNAs in human placenta and maternal serum. These miRNAs are secreted by fetal trophoblast cells within extracellular vesicles (EVs) and interact with the mother's immune cells, which has been proposed to be crucial for immunological tolerance at the placental-maternal interface. A key mechanism in preeclampsia, a multifactorial, multipath hypertensive pregnancy illness, is an immunological imbalance between the mother and the fetus.
View Article and Find Full Text PDFAntagonisation of Prokineticin Receptor-2 Attenuates Preeclampsia Symptoms.
J Cell Mol Med
January 2025
Interdisciplinary Research Institute of Grenoble, IRIG-Biosanté, University Grenoble Alpes, INSERM, CEA, UMR 1292, Grenoble, France.
Preeclampsia (PE) is the most threatening pathology of human pregnancy. Placenta from PE patients releases harmful factors that contribute to the exacerbation of the disease. Among these factors is the prokineticin1 (PROK1) and its receptor, PROKR2 that we identified as a mediators of PE.
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