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Recent cervical cancer incidence, stage at diagnosis, and mortality trends in Puerto Rico, 2001-2019. | LitMetric

AI Article Synopsis

  • Cervical cancer rates in Puerto Rico are on the rise, with a 1.6% annual increase in incidence from 2001 to 2019, particularly among women aged 25-64.
  • Data shows a significant rise in advanced-stage disease (4.5% per year), suggesting that this increase may not just be due to better diagnostics.
  • The stable mortality rates for this age group indicate a need for more effective prevention strategies and research to understand the causes behind these alarming trends.

Article Abstract

Background: Cervical cancer incidence is rising in Puerto Rico (PR). Whether the increase is real or reflective of increased diagnostic scrutiny remains unclear.

Methods: Using data from the PR Central Cancer Registry for 2001-2019, we estimated trends of hysterectomy-corrected cervical cancer incidence and mortality rates, overall, and by stage at diagnosis and age.

Results: Overall, cervical cancer incidence (per 100,000) increased 1.6%/year (95% CI, -0.5% to 3.8%) from 12.5 to 15.3, with a prominent increase in distant-stage disease (4.5%/year [95% CI, 1.6% to 8.0%]), particularly among screening age eligible (25-64-year-old) women (5.8%/year [95% CI, 2.1% to 10.6%]). Mortality rates in this age-group remained stable during the study period.

Conclusions: Increased occurrence of distant-stage disease among screening-eligible women is troubling and may reflect a real increase. Future research is needed to elucidate the factors underlying these trends. Improved prevention is also an urgent priority to reverse the rising cervical cancer incidence in PR.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11320972PMC
http://dx.doi.org/10.1186/s12916-024-03535-4DOI Listing

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