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Peripheral giant cell granuloma in a child with ectrodactyly-ectodermal dysplasia-cleft lip/palate syndrome: a case report. | LitMetric

AI Article Synopsis

  • - Ectrodactyly-ectodermal dysplasia-cleft lip/palate (EEC) syndrome affects ectodermal and mesodermal tissues, leading to issues like split hands/feet, ectodermal dysplasia, and orofacial clefting, requiring a multidisciplinary treatment approach.
  • - A case study details a young child with EEC syndrome who developed a peripheral giant cell granuloma (PGCG) in the lower jaw, which was surgically removed and followed up for 24 months with no recurrence.
  • - The findings emphasize the crucial role of dentists in diagnosing and managing oral health issues associated with EEC syndrome.

Article Abstract

Background: Ectrodactyly-ectodermal dysplasia-cleft lip/palate (EEC) syndrome mainly affects ectodermal and mesodermal tissues. It is usually manifested as split hands and feet, ectodermal dysplasia, and orofacial clefting, along with other signs and symptoms. A multidisciplinary approach to treatment is required, in which dentists play an important role in identifying and treating various oral conditions that may be genetically linked to or may be the result of EEC syndrome.

Case Presentation: The present case describes the oral condition of a young child suffering from EEC syndrome and presenting with peripheral giant cell granuloma (PGCG) in the mandibular anterior region. After obtaining a thorough medical and family history and a clinical examination, the lesion was surgically excised under local anesthesia. The patient was followed up at periodic intervals for the next twenty four months, during which no recurrence of the lesion was observed.

Conclusion: This report highlights the role of a dentist in the management of the oral conditions of patients suffering from EEC syndrome.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11321159PMC
http://dx.doi.org/10.1186/s12903-024-04585-zDOI Listing

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