The social and behavioral sciences have been increasingly using automated text analysis to measure psychological constructs in text. We explore whether GPT, the large-language model (LLM) underlying the AI chatbot ChatGPT, can be used as a tool for automated psychological text analysis in several languages. Across 15 datasets ( = 47,925 manually annotated tweets and news headlines), we tested whether different versions of GPT (3.5 Turbo, 4, and 4 Turbo) can accurately detect psychological constructs (sentiment, discrete emotions, offensiveness, and moral foundations) across 12 languages. We found that GPT ( = 0.59 to 0.77) performed much better than English-language dictionary analysis ( = 0.20 to 0.30) at detecting psychological constructs as judged by manual annotators. GPT performed nearly as well as, and sometimes better than, several top-performing fine-tuned machine learning models. Moreover, GPT's performance improved across successive versions of the model, particularly for lesser-spoken languages, and became less expensive. Overall, GPT may be superior to many existing methods of automated text analysis, since it achieves relatively high accuracy across many languages, requires no training data, and is easy to use with simple prompts (e.g., "is this text negative?") and little coding experience. We provide sample code and a video tutorial for analyzing text with the GPT application programming interface. We argue that GPT and other LLMs help democratize automated text analysis by making advanced natural language processing capabilities more accessible, and may help facilitate more cross-linguistic research with understudied languages.
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http://dx.doi.org/10.1073/pnas.2308950121 | DOI Listing |
J Virol
January 2025
SA MRC Antibody Immunity Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Parktown, Johannesburg, South Africa.
The Antibody Mediated Prevention (AMP) trials showed that passively infused VRC01, a broadly neutralizing antibody (bNAb) targeting the CD4 binding site (CD4bs) on the HIV-1 envelope protein (Env), protected against neutralization-sensitive viruses. We identified six individuals from the VRC01 treatment arm with multi-lineage breakthrough HIV-1 infections from HVTN703, where one variant was sensitive to VRC01 (IC < 25 ug/mL) but another was resistant. By comparing Env sequences of resistant and sensitive clones from each participant, we identified sites predicted to affect VRC01 neutralization and assessed the effect of their reversion in the VRC01-resistant clone on neutralization sensitivity.
View Article and Find Full Text PDFExpert Rev Pharmacoecon Outcomes Res
January 2025
Comprehensive Clinical Trials Unit, University College London, UK.
Objectives: Advanced therapy medicinal products (ATMPs) are transformative healthcare interventions, however, there has been limited research exploring their value. The objective of this study was to conduct a thematic analysis as part of a documentary analysis to identify value attributes of ATMPs.
Methods: As part of the NICE assessment processes in England, stakeholders are invited to provide comments on the technology.
JACC Adv
December 2024
Department of Neurology, National Cerebral and Cardiovascular Center (NCVC), Suita, Osaka, Japan.
R Soc Open Sci
January 2025
Mathematics Application Consortium for Science and Industry (MACSI), University of Limerick, Limerick, Ireland.
The analysis of social networks enables the understanding of social interactions, polarization of ideas and the spread of information, and therefore plays an important role in society. We use Twitter data-as it is a popular venue for the expression of opinion and dissemination of information-to identify opposing sides of a debate and, importantly, to observe how information spreads between these groups in our current polarized climate. To achieve this, we collected over 688 000 tweets from the Irish Abortion Referendum of 2018 to build a conversation network from users' mentions with sentiment-based homophily.
View Article and Find Full Text PDFJ Clin Sleep Med
January 2025
Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Study Objectives: To assess the effect of continuous positive airway pressure (CPAP) therapy on intraocular pressure in Obstructive sleep apnea (OSA) patients.
Methods: The search was performed in Ovid Medline and Embase database then followed by a manual bibliography search. Abstract search and screening were independently performed followed by eligible full-text versions reviewed.
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