Case: A 27-year-old man sustained chemical burns affecting 54% of his body caused by steam and acetic acid at a dyeing factory. He developed restricted bilateral elbow and shoulder motion because of heterotopic ossification (HO) beginning 3 months after the incident. The skin healed within 1 year, but ankylosis developed because of progressing ossification. We performed HO surgical excision in 4 stages. Two years after the final surgery, the function of both upper extremities had recovered.
Conclusion: For HO caused by severe burns, improvement in upper extremity function can be achieved even if surgery is performed after skin healing.
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http://dx.doi.org/10.2106/JBJS.CC.24.00117 | DOI Listing |
Surg Radiol Anat
January 2025
Department of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 75 Mikras Asias str, Goudi, Athens, 11527, Greece.
Background: The skull base ligaments have been extensively studied in the literature due to their clinical and surgical significance. The posterior petroclinoid fold (PPCNF) and petroclival ligament (PCVL) are two adjacent structures that have barely been studied and are frequently confused. The present study uses an innovative classification system to investigate the PPCNF and PCVL ossification patterns.
View Article and Find Full Text PDFChilds Nerv Syst
January 2025
Department of Neurosurgery, Xi'an Children's Hospital, Children's Hospital Affiliated to Xi'an, Jiaotong University, #69, Xijuyuan Lane, Lianhu District, Xi'an, 710043, Shaanxi, China.
Objective: Investigate the clinical features and treatment outcomes of neonatal cephalohematoma and ossified cephalohematoma.
Methods: A retrospective review was conducted on the clinical features of 281 children with neonatal cephalohematoma and ossified cephalohematoma managed over the previous 10 years.
Results: Of the neonatal cephalohematomas, 75 underwent puncture and aspiration, while 98 neonatal ossified cephalohematomas were treated with neurosurgery without cranioplasty.
Bone Res
January 2025
Department of Periodontics & Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
Bone morphogenetic proteins are essential for bone regeneration/fracture healing but can also induce heterotopic ossification (HO). Understanding accessory factors modulating BMP signaling would provide both a means of enhancing BMP-dependent regeneration while preventing HO. This study focuses on the ability of the collagen receptor, discoidin domain receptor 2 (DDR2), to regulate BMP activity.
View Article and Find Full Text PDFTuberk Toraks
December 2024
Department of Radiology, Tokat Gaziosmanpasa University Faculty of Medicine, Tokat, Türkiye.
Introduction: Diffuse pulmonary ossification (DPO) refers to the unusual formation of mature bone tissue within the lung parenchyma. It has been shown to be associated with a number of cardiac and chronic lung diseases. The relation between DPO and idiopathic pulmonary fibrosis (IPF) has been shown in the literature.
View Article and Find Full Text PDFBMC Biol
December 2024
College of Fisheries, Hubei Hongshan Laboratory/Key Lab of Freshwater Animal Breeding, Ministry of Agriculture and Rural Affairs/Engineering Research Center of Green Development for Conventional Aquatic Biological Industry in the Yangtze River Economic Belt, Ministry of Education, Huazhong Agricultural University, No. 1 Shizishan Street, Hongshan District, Wuhan, 430070, Hubei, China.
Background: Intermuscular bones (IBs) are segmental intramembranous ossifications located within myosepta. They share similarities with tendon ossification, a form of heterotopic ossification (HO). The mechanisms underlying IB formation remain incompletely understood.
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