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Role of Recombinant Proteins for Treating Rheumatoid Arthritis. | LitMetric

Role of Recombinant Proteins for Treating Rheumatoid Arthritis.

Avicenna J Med Biotechnol

Department of Biotechnology Engineering, Faculty of Medical Engineering, Shahab Danesh University, Qom, Iran.

Published: January 2024

Rheumatoid Arthritis (RA) is an autoimmune disease and chronic inflammatory disorder that affects joints and causes inflammation, pain, stiffness, and eventually progressive joint destruction. Approximately 1% of the world's population is estimated to suffer from RA, and if this disease is left untreated, it can lead to severe disability. Despite all the efforts and advances made by professionals in the field, there is currently no definitive treatment for RA, and most treatment strategies are aimed at relieving symptoms and improving patients' quality of life. One of the most promising current approaches is the use of recombinant proteins that target specific signaling pathways involved in the development of RA to alleviate symptoms and slow the progression of the disease. This article discusses the genetic and immunological factors that influence the development of RA, recombinant proteins, methods of using these proteins, approved drugs, and side effects associated with treating RA.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11316508PMC
http://dx.doi.org/10.18502/ajmb.v16i3.15739DOI Listing

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