AI Article Synopsis
- - Toluene is a common solvent known for its harmful effects, particularly on the nervous and blood systems, prompting a review of its impact on human platelet counts.
- - A search of 64 articles led to the selection of 14 studies involving 15,759 participants, primarily focusing on women exposed to toluene in their environment.
- - Key findings highlighted inconsistencies in results regarding platelet counts, issues with cross-contamination affecting data accuracy, and the need for more focused research on toluene exposure without other interfering substances.
Article Abstract
Toluene is a widely used solvent whose many toxic effects include neurological and hematological damage. This study reviewed evidence about the effects of toluene exposure on platelet count in humans. Three electronic databases and a digital library of theses and dissertations were searched using a specific strategy, yielding 64 articles, of which 14 were selected. These studies assessed a total of 15,759 participants, including 13,297 exposed individuals, mainly women exposed in an environmental setting. The major findings were: (1) conflicting results (positive, inverse, or no association), (2) cross-contamination with other substances, which impaired assessment of the relationship, and (3) a lack of studies. Thus, further research is needed on this topic, especially toluene exposure in isolation from associated substances.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11316532 | PMC |
| http://dx.doi.org/10.47626/1679-4435-2021-896 | DOI Listing |
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