Context: Diabetic eyes suffer from variety of complications including macular edema. Cataract surgery is the most commonly done procedure throughout the world and majority would be diabetics. As pseudophakic-cystoid macular edema (CME) is a known complication following cataract surgery, our study concentrated on finding the role of prophylactic topical nonsteroidal anti-inflammatory drugs (NSAIDs) on change in total macular volume (TMV) postcataract surgery in diabetic eyes.
Aims: To evaluate the role of NSAIDs on change in TMV postcataract surgery in diabetic eyes.
Settings And Design: Retrospective comparative study.
Subjects And Methods: Data were collected from the medical records department of our institute constituting diabetics undergoing cataract surgery from June-2021 to February-2022. Eighty diabetic eyes were divided into two groups: one group were given topical nepafenac drops and another who were not given. Demographic details, diabetic retinopathy stage, preoperative optical coherence tomography (OCT), and postoperative day (POD) 7, day 28, and 3 months OCT were collected. Statistical analysis was done to compare the change in TMV between both the groups.
Statistical Analysis Used: Student's -test and Chi-squared/Fisher's exact test were employed to find statistically significant differences between the two groups using SPSS-22.0 software.
Results: In our study, the mean age in the group with nepafenac was 60.93 ± 5.86 years and 31 (77.5%) had moderate nonproliferative diabetic retinopathy (NPDR), and in the group without nepafenac, the mean age was 58.53 ± 7.41 years and 30 (75%) had moderate NPDR. Majority of the individuals in the study group were known diabetic for 2-5 years. Change in TMV at POD 3 months among two groups was not statistically significant; = 0.758 ( < 0.05-significant).
Conclusions: Our study concluded that topical-NSAIDs played no role in postoperative period following cataract surgery with respect to change in TMV in diabetic eyes. Thus, prophylactic usage of topical-NSAIDs can be a burden on patient as it has no role in prevention of pseudophakic-CME in those with the duration of diabetes mellitus <5 years and with mild-to-moderate NPDR.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309548 | PMC |
| http://dx.doi.org/10.4103/ojo.ojo_26_23 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: Overexpression of tear matrix metalloproteinases-9 (MMP-9) on the ocular surface tissues has been reported to result in ocular surface damage. MMP-9 levels in tears have been listed as one of many tools for confirming dry eye disease (DED).
Objective: This investigation aimed to compare MMP-9 levels and ocular surface parameters in diabetic patients with and without DED.
Edible Berries-An Update on Nutritional Composition and Health Benefits-Part II.
Curr Nutr Rep
January 2025
Institute of Nutrition, Mahidol University, 999 Phutthamonthon 4 Road, Salaya, Nakhon Pathom, 73170, Thailand.
Purpose Of Review: Berries are a great source of fiber, polyunsaturated fatty acids, and beneficial secondary metabolites (polyphenols). Various phytochemicals present in berries (glycosidic-linked flavonoids, anthocyanins, etc.) provide potential health benefits to consumers.
View Article and Find Full Text PDFAssociation between the onset of diabetic retinopathy and thickness changes in the retina and choroid of children with type 1 diabetes: A three-year longitudinal study.
Ophthalmic Physiol Opt
January 2025
Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Purpose: To explore the longitudinal changes in retinal and choroidal thickness and their relation with the onset of type 1 diabetes mellitus (T1DM) in children.
Methods: Thirty-eight children with T1DM and 71 healthy controls were included in this 3-year longitudinal study. Ophthalmic and systemic examinations were conducted on each participant.
A pupillary image dataset: 10,000 annotated and 258,790 non-annotated images of patients with glaucoma, diabetes, and subjects influenced by alcohol, coupled with a segmentation performance evaluation.
Comput Biol Med
January 2025
Institute of Informatics, Federal University of Goiás, GO, Brazil.
The Pupillary Light Reflex (PLR) is the involuntary movement of the pupil adapting to lighting conditions. The measurement and qualification of this information have a broad impact in different fields. Thanks to technological advancements and algorithms, obtaining accurate and non-invasive records of pupillary movements is now possible, expanding practical applications.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates risk factors for proliferative vitreoretinopathy (PVR), a common complication after retinal detachment surgery.
- A large patient database was analyzed, identifying systemic (like age, gender, and smoking) and ocular (such as trauma and previous eye conditions) factors that correlate with increased PVR risk.
- The findings emphasize the importance of considering these risk factors in surgical planning and treatment to prevent PVR in patients with retinal detachment.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!