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| http://dx.doi.org/10.1016/j.jscai.2023.101253 | DOI Listing |
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Mental health and help-seeking behaviors among Mozambican youth: insights from a post-pandemic National Survey Amidst Internal Conflict.
Soc Psychiatry Psychiatr Epidemiol
January 2025
Research Center for Child Psychiatry, University of Turku, Turku, Finland.
Purpose: This study aimed to investigate the prevalence and sociodemographic determinants of major depressive disorder (MDD) and generalized anxiety disorder (GAD) among Mozambican youth aged 15-24 years, as well as their help-seeking behaviors.
Methods: Data from 8,154 youth participants in the 2022-23 Mozambique Demographic Health Survey were analyzed. MDD and GAD were assessed using the PHQ-9 and GAD-7 scales, respectively.
De novo transcriptome assembly and analysis during agarwood induction in Gyrinops versteegii Gilg. seedling.
Sci Rep
January 2025
Plant Science and Biotechnology Research Group, School of Life Sciences and Technology, Institut Teknologi Bandung, West Java, 40132, Indonesia.
Agarwood is a highly prized resinous wood produced by select members of the Thymelaeaceae plant family. Its formation in Aquilaria species has been expedited using various induction techniques, revealing insights into factors affecting the chemical constituents of artificially induced agarwood. Building on this, our research delved into the potential of another Thymelaeaceae member, Gyrinops versteegii, as an alternate agarwood source.
View Article and Find Full Text PDFYAT2150 is irresistible in Plasmodium falciparum and active against Plasmodium vivax and Leishmania clinical isolates.
Sci Rep
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Barcelona Institute for Global Health (ISGlobal, Hospital Clínic-University of Barcelona), Rosselló 149-153, Barcelona, 08036, Spain.
We recently characterized the potent antiplasmodial activity of the aggregated protein dye YAT2150, whose presumed mode of action is the inhibition of protein aggregation in the malaria parasite. Using single-dose and ramping methods, assays were done to select Plasmodium falciparum parasites resistant to YAT2150 concentrations ranging from 3× to 0.25× the in vitro IC of the compound (in the two-digit nM range) and performed a cross-resistance assessment in P.
View Article and Find Full Text PDFBone sarcomas and cancer predisposition syndromes.
Bull Cancer
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Department of Paediatric Oncology, Institut d'Haematologie et d'Oncologie Pédiatrique, Centre Léon-Bérard, Lyon, France. Electronic address:
Bone sarcomas, constituting less than 1% of malignant neoplasms across all age groups, are rare tumours possibly associated with genetic susceptibility syndromes. This review aims to provide recommendations for the detection of cancer predisposition syndromes associated with bone sarcomas and managing affected patients. Recommendations were formulated by a multidisciplinary working and reviewing group from GROUPOS and SFCE oncogenetic's group, including geneticists, oncologists, and radiologists.
View Article and Find Full Text PDFPrevalence, Diagnosis, and Management of Stress Urinary Incontinence in Women: A Collaborative Review.
Eur Urol
January 2025
Department of Urology, Freeman Hospital Newcastle-upon-Tyne UK; Translational and Clinical Research Institute, Newcastle University Newcastle-upon-Tyne UK.
Background And Objective: Stress urinary incontinence (SUI), defined as any involuntary leakage of urine associated with physical activity, remains underdiagnosed and undertreated. This review aims to provide an updated overview of the prevalence, diagnosis, and treatment of SUI in women, drawing upon recent evidence-based literature and clinical guidelines.
Methods: A systematic search of the MEDLINE database was conducted to identify only the most up-to-date and relevant studies published up to February 26, 2024, including the reference ESTER systematic review.
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