AI Article Synopsis
- Fat distribution, specifically android and gynoid adiposity, is linked to insulin resistance and sarcopenia in patients with type 2 diabetes mellitus (T2DM).
- A study involving 1086 T2DM patients assessed their body composition and found a notable prevalence of sarcopenia among the participants.
- Results indicated that those with higher android adiposity and android-to-gynoid ratios had a lower risk of sarcopenia, suggesting a potential protective effect against muscle loss.
Article Abstract
Background: Fat distribution plays an important role in impaired glucose tolerance. Android adiposity (ANDROID) and gynoid adiposity (GYNOID) have been proven to be linked with insulin resistance. A higher risk of sarcopenia is associated with type 2 diabetes mellitus (T2DM). In this study, ANDROID, GYNOID, and ANDROID to GYNOID ratios (A/G ratios) were evaluated in T2DM patients to determine if they were associated with sarcopenia.
Methods: We recruited 1086 T2DM patients, measured skeletal muscle index (SMI), ANDROID, GYNOID, and collected clinical data.
Results: T2DM patients with 119 male subjects had sarcopenia (20.24%), and 72 female subjects had sarcopenia (16.51%). All patients with T2DM who had high ANDROID and A/G ratios were at a reduced risk of sarcopenia. The SMI showed a correlation with ANDROID and A/G ratios among subjects with T2DM.
Conclusion: ANDROID and A/G ratios are inversely related to sarcopenia in T2DM patients.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11311146 | PMC |
| http://dx.doi.org/10.1177/20420188241269181 | DOI Listing |
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