Serum-beta-2-microglobulin was measured by radioimmunoassay in 25 patients with chronic lymphocellular leukaemia in stages III-IV according to the Rai classification. A significant positive correlation was found between the absolute lymphocyte count and the serum-beta-2-microglobulin level. No similar relationship was observed between the score indicative of organ infiltration and the beta-2-microglobulin valve. On the evidence of the results, the increased production of beta-2-microglobulin is attributed in the first place to the circulating lymphocytes. The assay has been found to provide a reliable indicator, suitable for the monitoring and evaluation of therapy.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Exploring the Relationships between Sex Hormones and Abdominal Muscle Area and Radiodensity in Postmenopausal Women: Insights from the Multi-Ethnic Study of Atherosclerosis.
Maturitas
January 2025
General Practice/Family Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
The relationships between sex hormone levels and muscle composition in postmenopausal women remain underexplored. To address this gap, we conducted a cross-sectional observational study utilizing data from the Multi-Ethnic Study of Atherosclerosis. Our analysis included 682 postmenopausal women aged 45-84 years with complete data, with a mean age of 63.
View Article and Find Full Text PDFEffect of School-Based Weekly Iron and Folic Acid Supplementation Program on the Serum Folate Status of Adolescent Girls in Sidama Region, Southern Ethiopia: Comparative Cross-Sectional Study.
Food Nutr Bull
January 2025
School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.
Background: In Ethiopia, a school-based weekly iron and folic acid supplementation (WIFAS) program is being implemented to reduce burden of anemia in adolescent girls. While the program's impact on iron levels is well-studied, there is limited evidence on its effect on folate status.
Objective: The study was aimed at assessing the effect of the WIFAS on serum folate levels of school adolescent girls in Sidama Region, Southern Ethiopia.
Maternal Omega-6/Omega-3 Concentration Ratio During Pregnancy and Infant Neurodevelopment: The ECLIPSES Study.
Nutrients
January 2025
Nutrition and Mental Health (NUTRISAM) Research Group, Universitat Rovira i Virgili, 43201 Reus, Spain.
Background: The balance of omega-6/omega-3 (-6/-3) is crucial for proper brain function as they have opposite physiological roles.
Objectives: To analyze the association between maternal serum ratios of -6/-3 in the first and third trimesters of pregnancy and the neurodevelopment of their children in the early days after birth in the population of Northern Spain's Mediterranean region.
Methods: Longitudinal study in which 336 mother-child pairs participated.
Salivary Flow Rate in Patients with Sjögren's Syndrome: Correlations with Salivary Gland Ultrasound Findings and Biomarkers of Disease Activity.
Int J Mol Sci
December 2024
Cardiology Department, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Sjögren's syndrome (SS) is a slowly progressive, chronic autoimmune inflammatory condition characterized by the affliction of the exocrine glands, with issues that derive from it markedly decreasing the quality of life of these patients. Salivary gland involvement can be identified through imaging methods. Among them, salivary gland ultrasonography (SGUS) is used as a diagnostic and prognostic tool in pSS.
View Article and Find Full Text PDFExpression and clinical significance of 25-hydroxyvitamin D, insulin-like growth factor 1, and beta-2 microglobulin in cognitive dysfunction after ischemic stroke in the elderly.
Neuroreport
January 2025
Department of Neurology, the Second Affiliated Hospital of Guizhou Medical University, Kaili, Guizhou Province, China.
Article Synopsis
- The study examined the relationship between serum levels of 25-hydroxyvitamin D, IGF-1, and beta-2 microglobulin in elderly patients with cognitive dysfunction after ischemic stroke.
- Data from 160 geriatric patients were analyzed, revealing that lower levels of 25-OH-VD and IGF-1 were linked to worse cognitive scores, while higher β2-MG levels correlated with greater cognitive decline.
- Factors such as diabetes, low education levels, age, and certain serum markers were identified as independent risk factors for developing cognitive dysfunction post-stroke, suggesting the importance of monitoring these serum levels in clinical settings.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!