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A systematic review of the socioeconomic impact of mechanical thrombectomy for acute ischemic stroke. | LitMetric

A systematic review of the socioeconomic impact of mechanical thrombectomy for acute ischemic stroke.

J Stroke Cerebrovasc Dis

Group of Applied Clinical Neurosciences, Department of Medicine, Dermatology and Toxicology, University of Valladolid, Valladolid, Spain; Stroke Unit & Stroke Program, Department of Neurology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.

Published: November 2024

AI Article Synopsis

  • Mechanical Thrombectomy (MT) is an effective treatment for severe acute ischemic stroke, but its access is hindered by economic barriers in many regions.
  • A systematic review following PRISMA guidelines analyzed the socioeconomic impact of MT compared to best medical therapy (BMT) using data from various scientific articles and online databases.
  • The findings indicated that MT is cost-saving in the long term, with a reasonable cost per quality-adjusted life year (QALY), suggesting that public policies should promote broader access to this treatment globally.

Article Abstract

Background: Mechanical Thrombectomy (MT) is an efficacious treatment for severe acute ischemic stroke patients. However, access to MT is limited in many parts of the world, partly due to economic barriers. The purpose of this systematic review is to provide an updated frame about the socioeconomic impact of MT.

Methods: To carry out this systematic review we used the PRISMA guidelines. We included scientific articles analyzing the socioeconomic impact of MT for acute ischemic stroke, in which MT was compared to best medical therapy (BMT). The online databases of Pubmed, Scopus and Web of Science were used as main sources of information. To carry out the comparative analysis, the incremental cost-effectiveness ratio (ICER) was used, relating the cost to quality-adjusted life-year (QALY). Risk of bias was assessed with the Consensus Health Economic Criteria (CHEC) and the Consolidated Health Economic Evaluation Reporting Standards (CHEERS).

Results: Eight hundred thirty-two studies were identified in this systematic review. As a result, studies that used cost-effectiveness analysis show that MT saves costs in the long term and cost-utility analysis show that the cost per QALY is reasonable with a mean ICER value of $14242.36/QALY.

Conclusions: MT has a favorable socioeconomic impact, as derived from cost-effectiveness and cost-utility analyses. Therefore, public policies should encourage the implementation of MT for stroke patients around the world.

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Source
http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2024.107906DOI Listing

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