Biomolecular condensates with liquid properties formed during viral infections.

Microbes Infect

Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, 91198 Gif-sur-Yvette, France. Electronic address:

Published: November 2024

During a viral infection, several membraneless compartments with liquid properties are formed. They can be of viral origin concentrating viral proteins and nucleic acids, and harboring essential stages of the viral cycle, or of cellular origin containing components involved in innate immunity. This is a paradigm shift in our understanding of viral replication and the interaction between viruses and innate cellular immunity.

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http://dx.doi.org/10.1016/j.micinf.2024.105402DOI Listing

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