AI Article Synopsis
- - Heart valve disease often requires patients to have several surgeries due to the wear and tear of artificial valves, indicating a need for better replacement options that can grow and repair themselves.
- - Allogeneic valve transplantation offers a potential solution by providing living valve replacements that could address these issues more effectively.
- - The authors suggest a new framework aimed at preserving and rehabilitating these living valves outside the body (ex vivo), to enhance their viability and functionality.
Article Abstract
Heart valve disease patients undergo multiple surgeries to replace structurally degraded valve prostheses, highlighting the need for valve replacements with growth and self-repair capacity. Given allogeneic valve transplantation's promise in meeting these goals by delivering a living valve replacement, we propose a framework for preserving and rehabilitating living valves ex vivo.
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| http://dx.doi.org/10.1016/j.medj.2024.07.004 | DOI Listing |
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