The Dressler-de Winter sign is an electrocardiogram (ECG) pattern characterized by upsloping ST-segment depression in leads V1-V6 followed by tall, hyperacute T waves, typically indicating an occlusion of the left anterior descending artery (LAD). We present a case involving an inferoposterior ST-segment elevation myocardial infarction (STEMI) with a variant of the de Winter sign, a concept of ST-segment continuum in the precordial leads. Despite initial ECG findings suggesting right coronary artery (RCA) or left circumflex artery (LCX) involvement, coronary angiography confirmed occlusion of the wrap-around LAD distal to the first septal (S1) and diagonal branch (D1) and revealed a left dominant system accompanied by a small non-dominant RCA. This case highlights the diagnostic complexity in accurately localizing the culprit artery in STEMI cases exhibiting the de Winter sign. Understanding such ECG variants is crucial for analyzing the mechanisms of acute ischemia and ensuring accurate assessment of the culprit vessel for effective revascularization.
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http://dx.doi.org/10.1016/j.jelectrocard.2024.153769 | DOI Listing |
Sci Rep
January 2025
Department of Biological, Geological, and Environmental Sciences, University of Bologna, Bologna, Italy.
The variability of East African short rains (October-December) has profound socioeconomic and environmental impacts on the region, making accurate seasonal rainfall predictions essential. We evaluated the predictability of East African short rains using model ensembles from the multi-system seasonal retrospective forecasts from the Copernicus Climate Change Service (C3S). We assess the prediction skill for 1- to 5-month lead times using forecasts initialized in September for each year from 1993 to 2016.
View Article and Find Full Text PDFAddict Biol
January 2025
Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany.
The ability of environmental cues to trigger alcohol-seeking behaviours is thought to facilitate problematic alcohol use. Individuals' tendency to attribute incentive salience to cues may increase the risk of addiction. We sought to study the relationship between incentive salience and alcohol addiction using non-preferring rats to model the heterogeneity of human alcohol consumption, investigating both males and females.
View Article and Find Full Text PDFClin Case Rep
December 2024
Division of Movement Science and Exercise Therapy, Department of Sport Science, Faculty of Medicine and Health Sciences Stellenbosch University Stellenbosch South Africa.
A 16-year-old male with hypermobility spectrum disorder (HSD) and Raynaud's phenomenon (RP) was referred to a clinical exercise physiologist (CEP) by their pediatric rheumatologist. The patient presented with arthralgia in the left knee and shoulder. Specifically, the left knee presented discomfort during activities of daily living (ADL), and the left shoulder had a reduced range of motion resulting from pain.
View Article and Find Full Text PDFOrv Hetil
November 2024
1 Betegápoló Irgalmasrend Budai Irgalmasrendi Kórháza, Kardiológia Budapest, Árpád fejedelem u. 7. II. em., 1023 Magyarország.
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