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Utilization of a Cortical Xenogeneic Membrane for Guided Bone Regeneration: A Retrospective Case Series. | LitMetric

Utilization of a Cortical Xenogeneic Membrane for Guided Bone Regeneration: A Retrospective Case Series.

J Clin Med

Oral Surgery Department, Assistance Publique des Hôpitaux de Marseille, 264 Avenue St Pierre, 13005 Marseille, France.

Published: August 2024

AI Article Synopsis

  • Guided bone regeneration (GBR) is effective for addressing bone defects, particularly in the challenging posterior mandibular region, using resorbable membranes that have a cortical component to increase rigidity.
  • A study was conducted on five patients using a porcine cortical membrane for GBR, showing significant horizontal (3.83 mm) and vertical (4.17 mm) bone gains after six months, with a high repeatability score.
  • Despite some patients experiencing pain that didn't respond to analgesics, no serious complications like infection were reported, indicating the membrane's potential but highlighting the need for further research to confirm its effectiveness.

Article Abstract

: Guided bone regeneration (GBR) is a reliable technique used in vertical and horizontal bone defects. The posterior mandibular region is an area limited by anatomic constraints. The use of resorbable membranes with a cortical component could compensate for the lack of rigidity of resorbable membranes without the complications of non-resorbable membranes. The aim of this study was to evaluate the mean bone gains of a xenogeneic cortical membrane in horizontal and vertical bone defects in comparison with other membranes in the literature. : A porcine cortical membrane was used to perform 7 GBR in the posterior mandibular region of five patients. Preoperative (T0) and six months postoperative (T1) cone beam computed tomography were superimposed to measure the horizontal and vertical bone gain. Implants were positioned at all sites, six months after GBR. Complications and bone resorption around the implants were also documented. : The mean horizontal and vertical bone gains were 3.83 ± 1.41 mm and 4.17 ± 1.86 mm, respectively. The analysis of repeatability was 0.997. As many as 40% of patients experienced pain refractory to analgesics. No exposure or infectious phenomenon was observed. : This xenogeneic cortical membrane seemed to provide interesting results in the regeneration of horizontal and vertical bone defects. Comparative and prospective studies are necessary to validate the effectiveness of this membrane.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11312857PMC
http://dx.doi.org/10.3390/jcm13154575DOI Listing

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