A case of malignant gastric glomus tumor and literature review: A case report.

Medicine (Baltimore)

Department of Gastrointestinal Colorectal Surgery, First Hospital of Jilin University, Changchun, China.

Published: August 2024

AI Article Synopsis

  • A malignant gastric glomus tumor (GGT) is a very rare and dangerous type of cancer that can affect people's health and lives.
  • A 49-year-old man found out he had this tumor after getting checked for gallbladder stones, and doctors performed surgery to remove it.
  • He successfully recovered and for 5 years after the surgery, there was no sign of the cancer returning, which is good news for treating similar cases in the future.

Article Abstract

Rationale: Malignant gastric glomus tumor (GGT) is an extremely rare malignant tumor of mesenchymal origin, it affects the patient's health and even threatens life. Malignant GGT with vascular invasion is even more rarely reported in the available literature without a prognostic study. So, in this case, we report a malignant GGT with vascular invasion and performed a 5-year postoperative follow-up. To the best of our knowledge, we report the first case of malignant GGT with vascular invasion without recurrence 5 years after surgery. This provides examples and lessons for the treatment of malignant GGT with vascular invasion.

Patient Concerns: A 49-year-old male was admitted to the hospital with gallbladder stones found on health check. After completing abdominal CT and ultrasound gastroscopy, a mass in the gastric antrum was found.

Diagnoses: The diagnosis of malignant GGT was confirmed by combination of postoperative pathology with positive immunohistochemistry for SMA, vimentin, synaptophysin, H-caldesmon, and calponin, mitosis > 10/50 HPF and moderate-to-severe nuclear atypia.

Interventions: On the 6th day of hospitalization, the patient underwent laparoscopic distal gastrectomy and cholecystectomy.

Outcomes: The patient was discharged successfully 1 week after surgery and was followed up for 5 years without recurrence.

Conclusion: Malignant GGT can be asymptomatic. For malignant GGT without distant metastasis, despite the presence of vascular invasion, negative margin surgery can still be the standard surgical radical treatment.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11315574PMC
http://dx.doi.org/10.1097/MD.0000000000039208DOI Listing

Publication Analysis

Top Keywords

malignant ggt
28
ggt vascular
16
vascular invasion
16
malignant
9
case malignant
8
malignant gastric
8
gastric glomus
8
glomus tumor
8
case report
8
ggt
8

Similar Publications

(1) Background and aim: Aloe arborescens Mill. (A. arborescens) is one of the most widely distributed species in the genus Aloe and has garnered widespread recognition for its anticancer properties.

View Article and Find Full Text PDF

Colorectal cancer (CRC) is the third most common cancer globally. Therefore, this study aims to examine data from the National Health Insurance Sharing Service (NHISS) to investigate factors influencing colon cancer incidence, focusing on key variables and optimal cutoff points. The patient cohort from the NHISS database included 1,120,377 individuals aged 1-85 years.

View Article and Find Full Text PDF

Background: As the primary organ of metabolism and detoxification, the liver may contribute to the pathogenesis of lung cancer. We aimed to illuminate the intricate link between liver function biomarkers and lung cancer risk, as well as delineate the role of smoking behavior within this association.

Methods: We investigated the associations of seven liver function biomarkers levels (alkaline phosphatase [ALP], alanine transaminase [ALT], total bilirubin [TBIL], albumin [ALB], gamma-glutamyltransferase [GGT], aspartate transaminase [AST], and total protein [TP]) with lung cancer risk across the UK Biobank (N = 337 499) through restricted cubic splines and Cox proportional hazards models.

View Article and Find Full Text PDF

Indications for and implications of germline genetic testing (GGT) in patients with prostate cancer have expanded over the past decade, particularly related to precision therapies and management. GGT has become the standard of care for many cancers such as breast, ovarian, colorectal, pancreatic, and metastatic prostate cancer, and it is imperative that patients be offered timely and equitable access to testing as it can inform patient-physician shared decision making for management of the current cancer as well as anticipatory guidance for disease progression. Additionally, GGT guides screening for and prevention of secondary malignancies for the patient and cascade testing for at-risk family members.

View Article and Find Full Text PDF

Carcinosarcomas of the bile ducts are very rare tumors. Their diagnosis and management remain difficult. We here report the case of a patient in whom the diagnosis was suspected due to cholestatic jaundice associated with a deterioration in general condition.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!