Purpose: To evaluate the impact of anterior chamber phakic intraocular lens (pIOL) on swept-source optical coherence tomography (SS-OCT) biometric measurements and IOL power calculation.
Methods: This retrospective analysis of 67 eyes of 49 patients with previous anterior chamber pIOL implantation analyzed the accuracy of automatic segmentation of the anterior surface of the crystalline lens and its impact on anterior chamber depth (ACD, measured from epithelium to lens), lens thickness measurements, and IOL power calculation. The sample was divided into two groups: correct detection of the anterior surface of the crystalline lens and inaccurate detection. Segmentation of eyes from the inaccurate detection group was manually corrected and ACD and lens thickness were calculated using ImageJ software. IOL power was calculated using 7 formulas for both measurements.
Results: The anterior surface of the crystalline lens was mis-identified in 13 (19.4%) eyes. ACD was underestimated (Δ -0.85 ± 0.33 mm, < .001) and lens thickness was overestimated (Δ +0.81 ± 0.25 mm, < .001). Manual correction changed the target spherical equivalent only in the Haigis formula ( = .009). After correction for segmentation bias, the Pearl DGS, Cooke K6, and EVO 2.0 formulas showed the lowest prediction error, with the Pearl DGS showing greatest accuracy within ±1.00 diopters of prediction error range (81.0%).
Conclusions: SS-OCT biometry misidentifies the anterior surface of the crystalline lens in a significant proportion, resulting in significant IOL power calculation error in the Haigis formula. Manual proofing of segmentation is mandatory in every patient with anterior chamber pIOL implantation. After correct segmentation, the Pearl DGS, Cooke K6, and EVO seem to be the best formulas. .
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http://dx.doi.org/10.3928/1081597X-20240716-01 | DOI Listing |
Doc Ophthalmol
March 2025
Department of Ophthalmology, Mie University School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Purpose: To report our flicker electroretinographic (ERG) findings in a patient who developed uveitis after treatment with immune checkpoint inhibitors (ICIs) for a metastatic malignant melanoma.
Methods: ERGs were used to monitor retinal physiology in a patient with ocular complications following systemic ICI administration. Flicker ERGs were recorded using the RETeval system before and after the ICI treatments.
J Glaucoma
March 2025
Department of Ophthalmology and Visual Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
Prcis: This study evaluated the 1-year efficacy and safety of a novel minimally invasive glaucoma surgery, gonio scratch, in reducing intraocular pressure of eyes with open-angle glaucoma and cataracts.
Purpose: To evaluate the 1-year efficacy and safety of phacoemulsification cataract extraction combined with gonio scratch (GS-Phaco), a novel minimally invasive glaucoma surgery, in patients with open-angle glaucoma and cataracts.
Patients And Methods: This prospective multicenter clinical trial was conducted at Hiroshima University, Yokoyama Retina Clinic, Kusatsu Eye Clinic, and Miyoshi Eye Clinic in Japan.
Graefes Arch Clin Exp Ophthalmol
March 2025
Department of Ophthalmology, Sisli Hamidiye Etfal Education and Research Hospital, Halaskargazi Street, 34371, Istanbul, Turkey.
Purpose: To evaluate the modified double-flanged technique in cases of subluxated foldable single-piece intraocular lenses (IOLs).
Methods: This retrospective study was conducted on 14 eyes of 14 patients.The following steps were performed in the surgical technique, respectively;the dislocated foldable single-piece IOL was repositioned into the anterior chamber, and the haptic was extracted through the corneal main incision.
Transl Vis Sci Technol
March 2025
Department of Medical Device Management and Research, SAIHST, Sungkyunkwan University, Seoul, Korea.
Purpose: This study investigated the relationship between aqueous humor (AH) viscosity and vascular endothelial growth factor-A (VEGF-A) in a corneal neovascularization (CNV) model.
Methods: Ten female New Zealand rabbits were divided into two groups (n = 5 each). CNV was induced by alkaline burns on the right corneas of group B, whereas group A underwent a sham procedure.
Clin Ophthalmol
March 2025
Ophthalmology Department, ULS São José, Lisboa, Portugal.
Purpose: To evaluate the effect on anterior chamber depth (ACD) and postoperative refractive prediction error (PE) of capsular tension ring (CTR) implantation during phacoemulsification in pseudoexfoliative (PEX) eyes.
Methods: Prospective case-control study of eyes submitted to uneventful cataract surgery, divided into three study groups: Group 1 - controls; Group 2 - PEX eyes without CTR implantation; Group 3 - PEX eyes with CTR implantation. Biometric data including ACD were measured preoperatively and 1-month postoperatively, using swept-source anterior segment optical coherence tomography (ANTERION, Heidelberg Engineering), and endothelial cell density (ECD) with specular microscopy.
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