AI Article Synopsis
- The study investigates the relationship between segmental infantile hemangiomas (SIH) and Blaschko lines, which are patterns of mosaicism observed on the skin.
- It involved comparing images of facial SIH from 8 patients to images of other facial dermatoses from 6 patients, using Photoshop to measure how much the lesions overlapped with Blaschko lines.
- The results showed that SIH had a significantly lower overlap with Blaschko lines (about 73%) compared to other conditions (about 90%), suggesting that SIH does not follow the typical mosaic pattern.
Article Abstract
Mosaicism has long been considered the underlying mechanism of segmental infantile hemangiomas (SIH). This was a prospective pilot case-control study conducted with the objective to quantify the percentage overlap of silhouettes of facial SIH with those of Blaschko lines (the most well studied archetypical pattern of mosaicism on face) as compared to other mosaic disorders on face. Lesional silhouettes of 8 patients with SIH (Group A) and 6 patients with other facial dermatosis known to have blaschkoidal distribution (Group B), were overlapped on a standardized template with Blaschkoidal lines on the frontal view of face. The alignment was done via the auto align tool of Photoshop and the percentage of overlap was calculated with an online image comparison software (IMGonline.com.ua). There was a significant difference in mean overlap in Group A (72.92 ± 15.6 %) as compared to Group B (90.1 ± 4.3%; =0.018). Hence, we concluded that facial SIH do not follow lines of Blaschko.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11305489 | PMC |
| http://dx.doi.org/10.4103/ijd.ijd_1089_23 | DOI Listing |
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