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Prevalence and aggravation of cervical spine instabilities in rheumatoid arthritis during over 10 years: a prospective multicenter cohort study.
Sci Rep
November 2024
Department of Orthopaedic Surgery, Kobe Rosai Hospital, 4-1-23 Kagoike-dori, Chuo-ku, Kobe, 651-0053, Japan.
Article Synopsis
- A multicenter cohort study was conducted to investigate the long-term prevalence and worsening of cervical spine instabilities in patients with rheumatoid arthritis (RA), involving 634 outpatients, with 233 followed for over 10 years.
- Cervical spine instability was assessed through specific measurements, with findings indicating that both vertical and subaxial subluxation increased significantly over time.
- Key predictors for worsening conditions included advanced joint damage, prolonged duration of RA, elevated C-reactive protein levels, and past joint surgery, highlighting the importance of managing disease activity to prevent further complications.
Epithelial inclusion cyst secondary to glaucoma surgery: A case series.
Arch Soc Esp Oftalmol (Engl Ed)
August 2024
Unidad de Glaucoma, Servicio de Oftalmología, Hospital Clínico San Carlos, Madrid, Spain.
Epithelial inclusion cysts (EIC) are a rare ocular disease and its physiopathology is not well-known. They consist on growths of ocular surface epithelial cells inside the anterior segment of the eye in the form of a cyst. To date several cases have been published in the literature, none of them related to glaucoma surgery.
View Article and Find Full Text PDFA novel entity of massive multifocal osteolyses in the elderly.
Bone Rep
June 2024
Institute of Human Genetics, Saarland University, D-66421 Homburg, Germany.
Osteolyses are common findings in elderly patients and most frequently represent malignant or locally aggressive bone tumors, infection, inflammatory and endocrine disorders, histiocytoses, and rare diseases such as Gorham-Stout syndrome. We here report on a novel entity of massive multifocal osteolyses in both shoulders, the right hip and left knee joint and the dens of an 83-year-old patient not relatable to any previously known etiopathology of bone disorders. The soft tissue mass is of myxoid stroma with an unspecific granulomatous inflammatory process, aggressively destroying extensive cortical and cancellous bone segments and encroaching on articulating bones in diarthrodial large joints.
View Article and Find Full Text PDFSevere Acro-osteolysis Mimicking Arthritis Mutilans in a Patient with Primary Hyperparathyroidism: A Case Report.
Curr Rheumatol Rev
July 2024
Department of Propedeutics of Internal Diseases, Medical University of Plovdiv, Medical Faculty, Plovdiv, Bulgaria.
Background: Primary hyperparathyroidism (PHPT) should be considered in the differential diagnosis of a patient with suspected secondary osteoporosis, and severe osteoporosis with multiple fractures is frequently the first clinical manifestation of the disease.
Case Presentation: Mutilating arthritis (arthritis mutilans) can be part of the clinical presentation of a number of rheumatic diseases, most commonly seen in psoriatic arthritis, rheumatoid arthritis, and juvenile idiopathic arthritis, but also in systemic lupus, systemic sclerosis, and multicentric reticulohistiocytosis. Evidence exists that subperiosteal and subchondral bone resorption, seen in PHPT, could induce the so-called 'osteogenic synovitis', which could eventually lead to the development of a secondary osteoarthritis with bone deformities.
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