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| http://dx.doi.org/10.1016/j.abd.2024.02.004 | DOI Listing |
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Update on actinomycetoma treatment: linezolid in the treatment of actinomycetomas due to spp and resistant to conventional treatments.
Expert Rev Anti Infect Ther
January 2025
Dermatology Department, Brighton General Hospital, University Hospitals Sussex NHS Foundation Trust, Brighton, UK.
Introduction: Mycetoma is a chronic granulomatous infection, common throughout tropical regions, and is considered a neglected disease that mostly affects impoverished populations. Mycetoma is divided into eumycetoma, caused by fungi, and actinomycetoma, caused by filamentous bacteria. Clinical presentation is distinctive, and making the diagnosis is usually not difficult; however, access to safe and effective treatments is a major challenge.
View Article and Find Full Text PDFDematiaceous Molds.
Infect Dis Clin North Am
December 2024
Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center, 1300 Morris Park Avenue, Belfer 610, Bronx, NY 10461, USA. Electronic address:
Article Synopsis
- Dematiaceous molds are dark environmental molds found worldwide, particularly in tropical and subtropical areas, with common types including Bipolaris, Cladophialophora, Exophiala, and Alternaria.
- These molds can cause a variety of diseases in both healthy and immunocompromised individuals, leading to issues like skin infections, allergic reactions, pneumonia, and sometimes serious systemic infections.
- Treatment generally involves antifungal medications such as itraconazole, voriconazole, or posaconazole, combined with measures to address the source of infection and reduce immune suppression, while efforts are underway to enhance diagnostic methods and treatment options due to high mortality rates associated with severe cases.
Deep Fungal Infections of Skin and Role of Histopathology in Diagnosis.
Indian J Dermatol
October 2024
Department of Dermatology, Institute of Child Health, Kolkata, India.
Introduction: Deep mycoses acquired by penetrating trauma to the skin can have varied and sometimes atypical morphological presentations resulting in diagnostic dilemmas and delay in treatment onset. Histopathology can be a useful tool in not only diagnosing but also differentiating various deep mycoses.
Aims And Objectives: To observe various morphological presentations and histopathological features of deep fungal infections.
Eumycetoma Caused by Aspergillus terreus: A Case Report and Literature Review.
Am J Trop Med Hyg
December 2024
Department of Dermatology, The Second Hospital of Jilin University, Changchun, People's Republic of China.
Mycetoma is a granulomatous disease of subcutaneous tissue that is caused by different species of aerobic filamentous bacteria (actinomycetoma) or fungi (eumycetoma). Mycetoma treatment depends on the causative pathogen, and it mainly consists of antimicrobial interventions or surgery. Aspergillus terreus is an etiologic agent of invasive aspergillosis and a rare cause of eumycetoma that is common in central and southern China.
View Article and Find Full Text PDFMycetoma Leading to Effusive Constrictive Pericarditis in an Immunocompetent Individual: A Rare Encounter.
Cureus
November 2024
Cardiothoracic Surgery, Lakeland Regional Health Medical Center, Lakeland, USA.
Nocardial infections are rare but serious, often leading to systemic and cardiopulmonary complications. This is the first reported case of causing constrictive pericarditis in an immunocompetent individual. We present a 37-year-old Caucasian female patient with no significant medical history who developed pericarditis symptoms after handling crates from China.
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