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Expert navigators deploy rational complexity-based decision precaching for large-scale real-world planning.
Proc Natl Acad Sci U S A
January 2025
Institute of Behavioural Neuroscience, Department of Experimental Psychology, University College London, London WC1H 0AP, United Kingdom.
Efficient planning is a distinctive hallmark of intelligence in humans, who routinely make rapid inferences over complex world contexts. However, studies investigating how humans accomplish this tend to focus on naive participants engaged in simplistic tasks with small state spaces, which do not reflect the intricacy, ecological validity, and human specialization in real-world planning. In this study, we examine the street-by-street route planning of London taxi drivers navigating across more than 26,000 streets in London (United Kingdom).
View Article and Find Full Text PDFNavigating Hope and Complexity: Turkish Parents' Experiences with Savior Siblings.
Turk J Haematol
January 2025
Acibadem Adana Hospital, Pediatric BMT Unit, Adana, Türkiye.
Background/aims: Preimplantation genetic diagnosis (PGD) with human leukocyte antigen (HLA) typing represents a significant advancement in treating inherited hematological disorders, particularly thalassemia major. This technology enables the birth of healthy children who can serve as compatible stem cell donors for their affected siblings. Turkey is a world leader in both PGD+HLA typing technology and hematopoietic stem cell transplantation from savior siblings born through PGD+HLA typing.
View Article and Find Full Text PDFEnhancing semantic segmentation for autonomous vehicle scene understanding in indian context using modified CANet model.
MethodsX
June 2025
Department of Computer Engineering, Pimpri Chinchwad College of Engineering, Nigdi, Pune 411044, India.
Recent advancements in artificial intelligence (AI) have increased interest in intelligent transportation systems, particularly autonomous vehicles. Safe navigation in traffic-heavy environments requires accurate road scene segmentation, yet traditional computer vision methods struggle with complex scenarios. This study emphasizes the role of deep learning in improving semantic segmentation using datasets like the Indian Driving Dataset (IDD), which presents unique challenges in chaotic road conditions.
View Article and Find Full Text PDFLocalized Drug Delivery in Different Gastrointestinal Cancers: Navigating Challenges and Advancing Nanotechnological Solutions.
Int J Nanomedicine
January 2025
Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, 11152, Egypt.
Different types of cancers affect the gastrointestinal tract (GIT), starting from the oral cavity and extending to the colon. In general, most of the current research focuses on the systemic delivery of the therapeutic agents, which leads to undesired side effects and a limited enhancement in the therapeutic outcomes. As a result, localized delivery within gastrointestinal (GI) cancers is favorable in overcoming these limitations.
View Article and Find Full Text PDFNavigating the depths: A comprehensive narrative review on depression in people with epilepsy.
Heliyon
January 2025
Department of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, 34212, Saudi Arabia.
Epilepsy presents a significant global health challenge, impacting millions worldwide. Alarmingly, over half of individuals living with epilepsy (PWE) also face concurrent medical conditions, with psychiatric complications, particularly depression, standing out as prevalent issues. The relationship between epilepsy and depression is complex and bidirectional, with approximately a quarter of adults with epilepsy receiving a diagnosis of depression.
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