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The emergent invasive serotype 4 ST10172 strain acquires vanG type vancomycin-resistance element: A case of a 66-year-old with bacteremic pneumococcal pneumonia. | LitMetric

AI Article Synopsis

  • * The patient, a 66-year-old, developed bacteremic pneumococcal pneumonia despite having received a vaccine designed to protect against pneumococcal infections.
  • * There has been an increase in cases of this particular strain in certain regions, and the detection of resistance genes raises concerns that need to be monitored closely.

Article Abstract

We report a single case of invasive pneumococcal disease (IPD) by serotype 4, multilocus sequence type 10172 (serotype 4/ST10172) isolate with vanG-type resistance genes and reduced vancomycin susceptibility. The isolate was recovered during 2022 from a 66-year-old resident with bacteremic pneumococcal pneumonia within a CDC Active Bacterial Core surveillance (ABCs) site hospital. The patient had received 23-valent pneumococcal polysaccharide vaccine and there was no evidence of concurrent or prior receipt of vancomycin in the previous year. Serotype 4/ST10172 IPD has shown increases within western ABCs sites and the recent acquisition of a vanG element warrants close monitoring of this lineage.

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Source
http://dx.doi.org/10.1093/infdis/jiae393DOI Listing

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