AI Article Synopsis
- Initial SARS-CoV-2 transmission peaked in densely populated areas of Kenya, gradually spreading to remote regions like Kajiado County, which struggle with inadequate healthcare.
- In a study from March 2020 to March 2022, dry blood spots (DBS) were collected from patients to detect SARS-CoV-2 IgG antibodies using ELISA, revealing a seropositivity rate of 7.3%.
- High seropositivity was found among the elderly and males, with the Mashuru and Meto health facilities showing the highest rates, indicating significant SARS-CoV-2 transmission in these underserved pastoralist communities.
Article Abstract
Initial transmission of severe acute respiratory syndrome virus-2 (SARS-CoV-2) was highest in densely populated regions of Kenya. Transmission gradually trickled down to the less densely populated, remote and underserved regions such as the pastoral regions of Kajiado County which are characterized by poor healthcare systems. Molecular assays that were pivotal for COVID-19 diagnosis were not available in these regions. Serology is an alternative method for retrospectively tracking the transmission of SARS-CoV-2 in such populations. Dry blood spots (DBS) were prepared from consenting patients attending six health facilities in Kajiado County from March 2020 to March 2022. Upon elution, we conducted an enzyme-linked immunosorbent assay (ELISA) for the detection of SARS-Cov-2 IgG antibodies. Of the 908 DBSs we analyzed, 706 (78%) were from female participants. The overall seropositivity to SARS-Cov-2 antibodies was 7.3% (95% CI 5.7-9.1). The elderly (over 60 years) and male participants had a high likelihood of testing positive for SAR-CoV-2 infections. Mashuru (15.6%, 14/90) and Meto (15%, 19/127) health facilities registered the highest proportion of seropositive participants. Evidence of SARS-CoV-2 transmission among pastoralists in the remote and underserved regions of Kajiado County was established by DBS sampling and serologic testing.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11309416 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0308318 | PLOS |
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Article Synopsis
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