COVID-19 in children: Clinical presentation and hospital course at a district hospital in South Africa.

S Afr J Infect Dis

Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

Published: July 2024

AI Article Synopsis

  • Limited data on South African children hospitalized with COVID-19 exist, particularly in lower-level district hospitals.
  • The study finds that young age, especially in infants exposed to HIV or born prematurely, significantly increases the risk of severe COVID-19 hospitalization.
  • A notable number of children admitted also have tuberculosis, indicating a concerning link between viral infections like COVID-19 and childhood tuberculosis.

Article Abstract

Unlabelled: Limited data exist on South African children hospitalised with COVID-19 in district hospitals. We describe the presentation and outcomes of children admitted to a level 1 and 2 hospital and compare this with children admitted to a level 2 and 3 hospital.

Contribution: This study highlights that young age is an important risk factor for hospitalisation with severe COVID-19. Infants with HIV exposure and prematurity are disproportionately represented among admissions. Furthermore, we notice a high number of children with current or new tuberculosis confirming the interplay between viral infections and childhood tuberculosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11304354PMC
http://dx.doi.org/10.4102/sajid.v39i1.580DOI Listing

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