Background: Barrier films or dressings were reported to be effective in preventing radiation dermatitis (RD) in breast cancer patients, but their comparative efficacy is unknown.
Methods: A systematic literature search was performed on Embase, MEDLINE and Cochrane CENTRAL Registry of Clinical Trials from inception to October 20, 2023. Randomised controlled trials (RCTs) comparing barrier films or dressings to the standard of care (SOC) or other interventions were included. We estimated summary odds ratios and mean differences using network meta-analysis with random effects. This study was registered with PROSPERO (ID: CRD42023475021).
Results: Fourteen RCTs met inclusion criteria. Six interventions were analysed: 3M™ Moisturizing Double Barrier Cream (MDBC), 3M™ No Sting Barrier Film (BF), Hydrofilm® (HF), Mepitel® Film (MF), Silver Leaf Nylon Dressing and StrataXRT®. HF, MF and StrataXRT® reduced the incidence of moist desquamation compared to SOC (HF: OR = 0.08; p = 0.02; MF: OR = 0.31 p < 0.01; StrataXRT®: OR = 0.22, p = 0.04). The ranking of agents from most to least effective in preventing moist desquamation according to P-scores was HF (92.5%), MF (78.5%), StrataXRT® (70.1%), BF (46.4%), Silver Leaf Nylon Dressing (24.9%), MDBC (22.9%) and SOC (14.7%). Only four RCTs on HF and MF included patient-reported outcome (PRO) assessments that allowed pooling for analysis. HF and MF were more effective in reducing pain, itchiness and burning sensation compared to SOC (p < 0.01 for all symptoms).
Conclusion: HF and MF were effective in preventing RD in breast cancer. Future RCTs should compare these interventions to effective cream preparations, such as topical corticosteroids.
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http://dx.doi.org/10.1007/s10549-024-07435-2 | DOI Listing |
Int J Biol Macromol
December 2024
School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huai'an 223003, Jiangsu, PR China. Electronic address:
In this study, smart films of EFS, EFS-SiO and EFS-SiO-CRE were successfully developed by using Euryale ferox starch (EFS), nano-SiO and Chinese rose extract (CRE). The Chinese rose flower had a high content of anthocyanins (1.73 mg/g) and CRE exhibited different colors in varying pH buffers (2-13).
View Article and Find Full Text PDFFood Chem
December 2024
College of Food Science and Technology, Bohai University, Jinzhou, Liaoning 121013, China. Electronic address:
This study focused on extracting nanocellulose from food processing waste to create a multi-functional edible coating for preserving grapes. Nanocellulose, in the form of short rods with diameters ranging from 30 to 130 nm, was extracted from soy hulls. Edible coatings were then prepared through an ion cross-linking method.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
State Key Laboratory of Polymer Materials Engineering of China (Sichuan University), Polymer Research Institute of Sichuan University, Chengdu 610065, China. Electronic address:
In order to improve the oxygen barrier performance of poly(lactic acid) (PLA), a simple and economical melt blending method was chosen and poly(vinyl alcohol) (PVOH) with excellent oxygen barrier was used as the reinforcing phase to meet high oxygen needs. To improve compatibility, PLA was grafted onto PVOH through L-LA ring opening polymerization to get poly(vinyl alcohol)-graft-poly(lactic acid) (PVOH-g-PLA). The films with high oxygen barrier performance were prepared by blending PLA with PVOH-g-PLA.
View Article and Find Full Text PDFSmall
December 2024
State Key Laboratory of Advanced Processing and Recycling of Nonferrous Metals, Lanzhou University of Technology, Lanzhou, 730050, China.
Carbon-based hole transport layer (HTL)-free perovskite solar cells (C-PSCs) receive a lot of attention because of their simplified preparation technology, low price, and good hydrophobicity. However, the Schottky junction formed at the interface between perovskite and carbon poles affects the photogenerated carrier extraction and conversion efficiency. In this paper, 4-trifluoromethyl-2-pyridinecarboxylic acid (TPCA) is used to modify the perovskite films.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea. Electronic address:
Improvement in film-forming properties of starch is critical for the wide application of environmentally friendly starch film. To enhance moisture barrier and mechanical properties of starch films, the formation of starch-lipid inclusion complex was promoted by partial debranching of starch and reaction at various temperature. The partially debranched potato starch was initially prepared with pullulanase, and the starch-lipid inclusion complex was subsequently produced with oleic acid at various reaction temperatures of 30, 50, and 70 °C.
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