AI Article Synopsis

  • - Malakoplakia is a rare type of inflammation mainly seen in the urinary bladders of dogs, with only one previous case reported in the colon.
  • - A 5-month-old spayed female French Bulldog was diagnosed with colonic malakoplakia after showing symptoms like chronic diarrhea and blood in feces, which did not improve with initial treatments.
  • - The dog showed significant recovery after 8 months of treatment with enrofloxacin, with noticeable progress after just 2 months.

Article Abstract

Malakoplakia is a rare granulomatous inflammation that has mainly been reported in the urinary bladder of dogs. Only one case of canine colonic malakoplakia has been reported to date; however, successful treatment of this disease has not been reported. Here, we report a case of colonic malakoplakia in a 5-month-old spayed female French Bulldog. The dog was referred to a veterinarian because of chronic diarrhea and mucinous blood feces; empirical treatment did not improve its condition. Histologically, numerous macrophages containing periodic acid-Schiff-positive granules infiltrated the lamina propria of the large intestine. Furthermore, targetoid basophilic inclusion bodies (Michaelis-Gutmann bodies) were observed. Complete clinical remission was achieved after 8 months of enrofloxacin treatment and favorable progress after 2 months of medication.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11422686PMC
http://dx.doi.org/10.1292/jvms.24-0166DOI Listing

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