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Structural and vascular assessment of the optic nerve head and macula in chronic Chagas disease.
Sci Rep
January 2025
Department of Ophthalmology, Federal University of São Paulo, São Paulo, SP, Brazil.
Chagas disease (CD), a parasitic infection, may have ocular repercussions in its cardiologic form, since a history of heart disease of other etiologies already has been established as a risk factor for neuropathies and maculopathies. The aim of the present study was to investigate preclinical structural and vascular optic nerve head (ONH) and macular parameters in patients with chronic CD. Nineteen patients with CD and 19 healthy subjects were evaluated with optical coherence tomography, optical coherence tomography angiography, and Laguna ONhE® software.
View Article and Find Full Text PDFEffect of eHMI-equipped automated vehicles on pedestrian crossing behavior and safety: A focus on blind spot scenarios.
Accid Anal Prev
January 2025
Jiangsu Key Laboratory of Urban ITS, Southeast University, Nanjing 211189, China; Jiangsu Province Collaborative Innovation Center of Modern Urban Traffic Technologies, Nanjing 211189, China; School of Transportation, Southeast University, Nanjing 211189, China. Electronic address:
Blind spot collisions are a critical and often overlooked threat to pedestrian safety, frequently resulting in severe injuries. This study investigates the impact of automated vehicles equipped with external human-machine interfaces (eHMIs) on pedestrian crossing behavior and safety, focusing on scenarios where AVs create mutual blind spots between pedestrians and adjacent traffic. A virtual reality experiment with 51 participants simulated crossing situations in front of yielding trucks with obstructed pedestrian visibility, featuring three eHMIs: 'Walk,' 'Don't Walk,' and 'Caution! Blind Spots'.
View Article and Find Full Text PDFStructural reversal of disc cupping measured in Bruch's membrane opening-based OCT morphometry after PRESERFLO microshunt implantation for open-angle glaucoma.
BMC Ophthalmol
January 2025
Department of Ophthalmology, Medical Faculty, University Hospital of Cologne, Kerpener Strasse 62, 50937, Cologne, Germany.
Background/ Aims: To analyze the longitudinal change in Bruch's membrane opening minimal rim width (BMO-MRW) and peripapillary retinal nerve fiber layer (pRNFL) thickness using optical coherence tomography (OCT) after implantation of a PRESERFLO® microshunt for surgical glaucoma management in adult glaucoma patients.
Methods: Retrospective data analysis of 59 eyes of 59 participants undergoing implantation of a PRESERFLO microshunt between 2019 and 2022 at a tertiary center for glaucoma management. Surgical management included primary temporary occlusion of the glaucoma shunt to prevent early hypotony.
Utility of Papilledema for Detection of Elevated Intracranial Pressure in Craniosynostosis.
J Craniofac Surg
November 2024
Department of Plastic Surgery, University of Texas Southwestern Medical Center.
Papilledema is swelling of the optic disk due to fluid accumulation around the optic nerve and is commonly used to detect increased intracranial (ICP) in craniosynostosis. This study aimed to assess the prevalence and utility of papilledema detection in patients with single-suture, multi-suture, and syndromic craniosynostosis and the differences before and after surgical intervention. A retrospective review of ophthalmology examinations of patients diagnosed with craniosynostosis treated between 2008 and 2023 was performed.
View Article and Find Full Text PDFHOMA-IR value in predicting retinal microvascular dysfunction.
Narra J
December 2024
Department of Clinical Pathology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Obesity and retinal microvasculature dysfunction are linked and impact visual acuity. The aim of this study was to determine the relationship between the HOMA-IR score and the presence of vascular dysfunction (capillary perfusion and flux index) of the optic nerve head (ONH) of the retina in obese patients and to determine its diagnostic performance to predict vascular dysfunction. A case-control study was conducted in 2022 involving individuals from obese and non-obese groups.
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