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Reconstruction and Revision of a Large Multisubunit Defect of the Cheek, Nose, and Lip.
Dermatol Surg
January 2025
Department of Dermatology, Mayo Clinic, Rochester, Minnesota.
A dual role of Cohesin in DNA DSB repair.
Nat Commun
January 2025
Department of Hematopoietic Biology & Malignancy, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Cells undergo tens of thousands of DNA-damaging events each day. Defects in repairing double-stranded breaks (DSBs) can lead to genomic instability, contributing to cancer, genetic disorders, immunological diseases, and developmental defects. Cohesin, a multi-subunit protein complex, plays a crucial role in both chromosome organization and DNA repair by creating architectural loops through chromatin extrusion.
View Article and Find Full Text PDFReconstruction of a Multisubunit Defect of the Nasal Ala and Medial Cheek.
Dermatol Surg
January 2025
All authors are affiliated with the Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, NY.
Reconstruction of a Multisubunit Nasal Defect With Loss of Structural Support.
Dermatol Surg
December 2024
Division of Dermatology, Baylor University Medical Center, Dallas, Texas.
The Nasolabial Flap in Nose Reconstruction: Tips and Tricks Towards Expanded Usage and Optimized Cosmesis.
Plast Surg (Oakv)
November 2024
Plastic and Reconstructive Surgery Unit, ASST Papa Giovanni XXIII, Bergamo, Italy.
The nose is the most critical aesthetic element of the face and even the smallest loss of substance can create a deformity of concern. The forehead flap has been the workhorse for nasal reconstruction for centuries but requires multiple surgical steps and leads to prominent donor-site scarring. The nasolabial flap allows a single-step reconstruction with a donor-site scar concealed in the nasolabial crease but is conventionally designated for small defects involving the ala.
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