AI Article Synopsis
- Naphthalocyanine-based agents are promising for cancer treatment using photodynamic therapy, but their effectiveness is limited by how deep the laser can penetrate into tissues.
- The study utilizes F-FDG (a type of imaging agent) as an internal light source to activate silicon naphthalocyanine nanoparticles, enhancing their ability to generate oxygen and combat tumors.
- This approach helps overcome the limitations of using external lasers, potentially leading to more effective tumor suppression.
Article Abstract
Naphthalocyanine-based agents exhibit huge potential in photodynamic therapy, yet their photodynamic performance is restricted by the penetration depth of the external laser. Herein, we employed F-FDG as an internal light source to excite silicon naphthalocyanine nanoparticles to simultaneously circumvent radiative transition and boost O generation for tumor suppression.
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| http://dx.doi.org/10.1039/d4cc03281k | DOI Listing |
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