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Minoxidil Intoxication: A Case of Refractory Shock With Prolonged Supportive Care.
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Emergency Department, Centre Hospitalier Universitaire Tivoli, La Louvière, BEL.
Minoxidil, commonly used as a topical agent for alopecia, is occasionally used for refractory hypertension due to its antihypertensive properties. We report a rare case of massive minoxidil intoxication leading to refractory vasoplegic shock in a 24-year-old male. The patient ingested 120 mL of 5% minoxidil solution, resulting in vasoplegic shock.
View Article and Find Full Text PDFLancereaux, diabète maigre, and diabète gras revisited.
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Diabète Maigre and Diabète Gras Revisited.
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A Story of Serendipities: From Phlorizin to Gliflozins.
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June 2023
From the Gazi University Faculty of Medicine, Department of Nephrology, Ankara, Turkey.
Diabetes has been acknowledged since ancient times. However, it was only during the late 1800s that we realized that the primary organ for blood glucose regulation was the pancreas. The 20th century witnessed insulin purification, which revolutionized the treatment of diabetes maigre; this was followed by the development of oral antidiabetic drugs.
View Article and Find Full Text PDFClinical characteristics and outcome of 318 families with familial monoclonal gammopathy: A multicenter Intergroupe Francophone du Myélome study.
Am J Hematol
February 2023
HU PITIE SALPETRIERE APHP, Paris, France.
Article Synopsis
- Familial forms of monoclonal gammopathy, including multiple myeloma (MM) and Monoclonal Gammopathy of Undetermined Significance (MGUS), are rare, with MGUS being more commonly observed and sometimes advancing to MM.
- A study identified 318 families with multiple cases of monoclonal gammopathy, highlighting potential genetic links and family clusters with parent-child and sibling cases.
- Despite some genetic similarities, familial cases generally present similarly to sporadic cases but show a better prognosis, with longer median survival rates for those with familial MM.
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