Unlabelled: The field of microrobotics has emerged as a promising area of research with significant applications in biomedicine, both in vitro and in vivo, such as targeted cargo delivery, microsurgery, and cellular manipulation. Microrobots actuated with multiple modalities have the potential for greater adaptability, robustness, and capability to perform various tasks. Modular units that can reconfigure into various shapes, create structures that may be difficult to fabricate as one whole unit, and be assembled on-site, could provide more versatility by assembly and disassembly of units on demand. Such multi-modal modular microrobots have the potential to address challenging applications. Here, we present a biocompatible cylindrical microrobot with a dome-shaped cavity. The microrobot is actuated by both magnetic and acoustic fields and forms modular microstructures of various shapes. We demonstrate the use of these microrobots for cellular manipulation by creating patterns on a surface.
Supplementary Information: The online version contains supplementary material available at 10.1007/s12213-024-00175-y.
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http://dx.doi.org/10.1007/s12213-024-00175-y | DOI Listing |
ACS Appl Mater Interfaces
December 2024
State Key Laboratory of Robotics and Systems, Harbin Institute of Technology, Harbin 150001, China.
Through billions of years of evolution, small and microorganisms have come to possess distinctive shape-morphing abilities to live in complex fluid environments. However, fabricating milliscale programmable machines with shape-morphing ability often involves complicated architectures requiring arduous fabrication processes and multiple external stimuli. Here, milliscale programmable machines with reconfigurable structures and extensible sizes are proposed based on the sequential assembly of simple Janus disks at liquid surfaces.
View Article and Find Full Text PDFJ Microbio Robot
August 2024
Department of Mechanical Engineering, University of Delaware, Newark, 19711 DE USA.
Unlabelled: The field of microrobotics has emerged as a promising area of research with significant applications in biomedicine, both in vitro and in vivo, such as targeted cargo delivery, microsurgery, and cellular manipulation. Microrobots actuated with multiple modalities have the potential for greater adaptability, robustness, and capability to perform various tasks. Modular units that can reconfigure into various shapes, create structures that may be difficult to fabricate as one whole unit, and be assembled on-site, could provide more versatility by assembly and disassembly of units on demand.
View Article and Find Full Text PDFSmall
November 2024
School of Mechanical Engineering, Purdue University, West Lafayette, IN, 47907, USA.
Microrobots show great potential in biomedical applications such as drug delivery and cell manipulations. However, current microrobots are mostly fabricated as a single entity and type and the tasks they can perform are limited. In this paper, modular microrobots, with an overall size of 120 µm × 200 µm, are proposed with responsive mating components, made from stimuli-responsive hydrogels, and application specific end-effectors for microassembly tasks.
View Article and Find Full Text PDFInt Conf Manip Autom Robot Small Scales
October 2023
Department of Mechanical Engineering, University of Delaware, Newark, DE 19716 USA.
Microrobots have emerged as promising tools for biomedical and in vivo applications, leveraging their untethered actuation capabilities and miniature size. Despite extensive research on diversifying multi-actuation modes for single types of robots, these tiny machines tend to have limited versatility while navigating different environments or performing specific tasks. To overcome such limitations, self-assembly microstructures with on-demand reconfiguration capabilities have gained recent attention as the future of biocompatible microrobotics, as they can address drug delivery, microsurgery, and organoid development processes.
View Article and Find Full Text PDFSci Adv
December 2023
Department of Mechanical and Automation Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China.
The magnetic microrobots promise benefits in minimally invasive cell-based therapy. However, they generally suffer from an inevitable compromise between their magnetic responsiveness and biomedical functions. Herein, we report a modularized microrobot consisting of magnetic actuation (MA) and cell scaffold (CS) modules.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!